Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14818604 | 0.84 | CYP2D6 (0.38) | CYP2D6 | |
| SCHEMBL26788658 | 0.81 | BDKRB2 (0.31) | — | |
| SCHEMBL25854982 | 0.78 | ALDH1A1 (0.42) | CYP2D6 | |
| SCHEMBL22317566 | 0.77 | CYP2D6 (0.36) | CYP2D6 | |
| SCHEMBL27277321 | 0.75 | — | — | |
| SCHEMBL25812958 | 0.75 | CYP2D6 (0.33) | CYP2D6 | |
| SCHEMBL25753435 | 0.74 | CYP2D6 (0.38) | CYP2D6 | |
| SCHEMBL25909806 | 0.74 | CYP2D6 (0.34) | CYP2D6 | |
| SCHEMBL24350893 | 0.73 | CYP2D6 (0.32) | CYP2D6 | |
| SCHEMBL19570537 | 0.71 | SLC6A2 (0.34) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220134-A1 | PYRAZINE DERIVATIVES AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |