Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27008050 | 0.88 | ALDH1A1 (0.31) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL17260845 | 0.82 | ALDH1A1 (0.34) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL25435839 | 0.82 | HPGD (0.31) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL27008088 | 0.81 | GRM4 (0.31) | — | |
| SCHEMBL25438598 | 0.78 | ALDH1A1 (0.31) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL27008083 | 0.78 | ALDH1A1 (0.31) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL27008199 | 0.77 | SMPD3 (0.32) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL25151318 | 0.77 | IRAK4 (0.33) | — | |
| SCHEMBL27008131 | 0.76 | ALDH1A1 (0.30) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL26664321 | 0.75 | KDM4E (0.39) | KDM4ETSHRALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225244-A1 | HETEROCYCLIC COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | BIOGEN MA INC. (US) | 2023-11-23 | — | — | WO | disclosed |