Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.50 |
| ▸ | IL1RN | P18510 | 3/20 | 0.50 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | NPY4R | P50391 | 2/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.43 |
| ▸ | ESRRB | O95718 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26817916 | 0.93 | ALDH1A1 (0.59) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL26817967 | 0.83 | ALDH1A1 (0.48) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL26817913 | 0.83 | ALDH1A1 (0.48) | TSHRALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL26817898 | 0.83 | KMT2A (0.48) | TSHRALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL26817902 | 0.81 | KMT2A (0.46) | TSHRALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL26817931 | 0.81 | KMT2A (0.46) | TSHRALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL26817933 | 0.79 | ALDH1A1 (0.44) | TSHRALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL26817908 | 0.78 | KMT2A (0.43) | TSHRALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL26817750 | 0.77 | TSHR (0.56) | TSHRALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL930562 | 0.77 | IL1RN (0.57) | TSHRALDH1A1THRBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382946-A1 | POLYPEPTIDE OR PROTEIN DIRECTIONAL MODIFICATION METHOD BASED ON SULFHYDRYL-ALKENYL AZIDE COUPLING | Changzhou University (CN) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382946-A1 | POLYPEPTIDE OR PROTEIN DIRECTIONAL MODIFICATION METHOD BASED ON SULFHYDRYL-ALKENYL AZIDE COUPLING | PTMS, CBS, CHAMP1 | TSHR 1863/4885ALDH1A1 1808/4885THRB 855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.