SCHEMBL26820155

SCHEMBL26820155

FC(F)(F)c1ccc(-c2ccc(-c3cccc(-c4ccc5ccccc5c4)c3)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 5/20 0.61
HSD17B1 P14061 1/20 0.52
HSD17B2 P37059 1/20 0.52
ESR1 P03372 3/20 0.50
ESR2 Q92731 3/20 0.50
AGXT P21549 1/20 0.49
DHODH Q02127 1/20 0.47
PGR P06401 1/20 0.45
CYP17A1 P05093 1/20 0.44
CYP19A1 P11511 1/20 0.44
CYP11B1 P15538 1/20 0.44
CYP11B2 P19099 1/20 0.44
ALOX5 P09917 1/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
BACE1 P56817 1/20 0.43
PTPN1 P18031 1/20 0.43
GLO1 Q04760 1/20 0.42
DGAT1 O75907 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26830018 1.00 KIF11 (0.61) KIF11HSD17B1HSD17B2ESR1ESR2
SCHEMBL26820138 0.94 KIF11 (0.61) KIF11HSD17B1HSD17B2ESR1ESR2
SCHEMBL22389484 0.94 KIF11 (0.61) KIF11HSD17B1HSD17B2ESR1ESR2
SCHEMBL26548374 0.94 KIF11 (0.61) KIF11HSD17B1HSD17B2ESR1ESR2
SCHEMBL26820145 0.94 KIF11 (0.61) KIF11HSD17B1HSD17B2ESR1ESR2
SCHEMBL26547922 0.94 KIF11 (0.61) KIF11HSD17B1HSD17B2ESR1ESR2
SCHEMBL26548556 0.92 KIF11 (0.59) KIF11HSD17B1HSD17B2ESR1ESR2
SCHEMBL26548865 0.92 KIF11 (0.59) KIF11HSD17B1HSD17B2ESR1ESR2
SCHEMBL26820159 0.91 PGR (0.55) KIF11HSD17B1HSD17B2ESR1ESR2
SCHEMBL26820287 0.91 PGR (0.55) KIF11HSD17B1HSD17B2ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4282861-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME Lapto Co., Ltd. (KR) 2023-11-29 EP disclosed