⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14759991 | 1.00 | — | — | |
| SCHEMBL27342 | 0.94 | — | — | |
| SCHEMBL28544 | 0.89 | — | — | |
| SCHEMBL8507540 | 0.89 | — | — | |
| SCHEMBL6747192 | 0.89 | — | — | |
| SCHEMBL1443200 | 0.89 | — | — | |
| SCHEMBL1003911 | 0.84 | — | — | |
| SCHEMBL31017583 | 0.84 | ALDH1A1 (0.30) | — | |
| SCHEMBL1812050 | 0.84 | — | — | |
| SCHEMBL19971177 | 0.84 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260138970-A1 | MODULATORS OF THE CALCIUM SIGNALING CASCADE | FONDAZIONE TELETHON ETS (IT) | 2026-05-21 | — | — | US | claimed |
| EP-4608397-A1 | MODULATORS OF THE CALCIUM SIGNALING CASCADE | Fondazione Telethon ETS (IT) | 2025-09-03 | — | — | EP | claimed |
| CN-118354999-A | Pyridazine-1 (6H) -6-oxo compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-07-16 | — | — | CN | claimed |
| WO-2024089296-A1 | MODULATORS OF THE CALCIUM SIGNALING CASCADE | FONDAZIONE TELETHON ETS (IT) | 2024-05-02 | — | — | WO | claimed |
| CN-117881664-A | Cycloalkyl 3-oxopiperazine carboxamides and cycloheteroalkyl 3-oxopiperazine carboxamides as NAV1.8 inhibitors | 默沙东有限责任公司 | 2024-04-12 | — | — | CN | claimed |
| EP-4334293-A1 | CYCLOALKYL 3-OXOPIPERAZINE CARBOXAMIDES AND CYCLOHETEROALKYL 3-OXOPIPERAZINE CARBOXAMIDES AS NAV1.8 INHIBITORS | Merck Sharp & Dohme LLC (US) | 2024-03-13 | — | — | EP | claimed |
| WO-2023134698-A1 | PYRIDAZINE-1(6H)-6-OXO COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 深圳信立泰药业股份有限公司 | 2023-07-20 | — | — | WO | claimed |
| US-20220380338-A1 | CYCLOALKYL 3-OXOPIPERAZINE CARBOXAMIDES AND CYCLOHETEROALKYL 3-OXOPIPERAZINE CARBOXAMIDES AS NAV1.8 INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2022-12-01 | — | — | US | claimed |
| WO-2022235859-A1 | CYCLOALKYL 3-OXOPIPERAZINE CARBOXAMIDES AND CYCLOHETEROALKYL 3-OXOPIPERAZINE CARBOXAMIDES AS NAV1.8 INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2022-11-10 | — | — | WO | claimed |
| EP-3642264-A1 | CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF | Momentive Performance Materials Inc. (US) | 2020-04-29 | — | — | EP | claimed |
| EP-2234954-B1 | TETRASUBSTITUTED BENZENES | ENVIVO PHARMACEUTICALS INC (US) | 2015-02-18 | — | — | EP | claimed |
| US-8664249-B2 | Tetrasubstituted benzenes | ENVIVO PHARMACEUTICALS, INC. (US) | 2014-03-04 | — | — | US | claimed |
| US-20130165486-A1 | TETRASUBSTITUTED BENZENES | ENVIVO PHARMACEUTICALS, INC. (US) | 2013-06-27 | — | — | US | claimed |
| US-8022205-B2 | Pyrimidine derivatives as PI3K inhibitor and use thereof | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2011-09-20 | — | — | US | claimed |
| US-20100069629-A1 | PYRIMIDINE DERIVATIVES AS PI3K INHIBITOR AND USE THEREOF | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2010-03-18 | — | — | US | claimed |
| EP-2050749-A1 | PYRIMIDINE DERIVATIVE AS PI3K INHIBITOR AND USE THEREOF | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-04-22 | — | — | EP | claimed |
| EP-0432132-B1 | A method for preparation of mono- and diisopropylnaphthalenes | TOSOH CORP (JP) | 1993-12-08 | — | — | EP | claimed |
| US-5026941-A | Catalytic alkylation of naphthalene and/or 2-isopropyl-naphthalene in the presence of a saturated polycarbocyclic compound to yield 2,6- and 2,7-diisopropylnaphthalene | TOSHO CORPORATION (JP) | 1991-06-25 | — | — | US | claimed |
| EP-0432132-A1 | A method for preparation of mono- and diisopropylnaphthalenes | Tosoh Corporation (JP) | 1991-06-12 | — | — | EP | claimed |
| EP-0338292-A1 | A Method for the Preparation of Diisopropyluaphthalenes | Tosoh Corporation (JP) | 1989-10-25 | — | — | EP | claimed |