Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.35 |
| ▸ | MMP3 | P08254 | 3/20 | 0.35 |
| ▸ | MMP9 | P14780 | 3/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10402868 | 0.81 | MAOA (0.57) | MAOAMAOBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL3441777 | 0.76 | MAOA (0.61) | MAOAMAOBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL3614462 | 0.75 | MAOA (0.59) | MAOAMAOBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL3614466 | 0.75 | MAOA (0.59) | MAOAMAOBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL28498239 | 0.75 | MAOA (0.59) | MAOAMAOBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL24688181 | 0.75 | MAOA (0.64) | MAOAMAOBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL1539929 | 0.75 | MAOA (0.64) | MAOAMAOBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL25274884 | 0.74 | MAOA (0.53) | MAOAMAOBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL25236742 | 0.74 | MAOA (0.53) | MAOAMAOBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL7529147 | 0.73 | MAOA (0.68) | MAOAMAOBMTNR1AMTNR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220425-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |