Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2539868 | 0.87 | MAPT (0.62) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8691287 | 0.86 | HTR1A (0.64) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8229566 | 0.85 | MAPT (0.87) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL2534045 | 0.83 | MAPT (0.69) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL5148298 | 0.82 | MAPT (0.68) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL2536283 | 0.81 | GAA (0.67) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL31660992 | 0.81 | GAA (0.67) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL5148291 | 0.81 | MAPT (0.70) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL650217 | 0.79 | MAPT (0.86) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL2535334 | 0.79 | GAA (0.73) | MAPTMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226381-A1 | INDOLE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海英诺富成生物科技有限公司 | 2023-11-30 | — | — | WO | disclosed |