Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 6/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26866627 | 0.84 | FPR2 (0.32) | FPR2SMN1; SMN2 | |
| SCHEMBL10667885 | 0.76 | KMT2A (0.47) | MAPT | |
| SCHEMBL28173216 | 0.75 | KMT2A (0.38) | FPR2MAPT | |
| SCHEMBL26196835 | 0.74 | KDR (0.32) | FPR2 | |
| SCHEMBL3592024 | 0.71 | FPR2 (0.43) | FPR2SMN1; SMN2 | |
| SCHEMBL26696007 | 0.71 | FPR2 (0.36) | FPR2 | |
| Hydrochloric Acid SCHEMBL26696076 | 0.70 | FPR2 (0.36) | FPR2SMN1; SMN2 | |
| SCHEMBL31252039 | 0.70 | TLR8 (0.43) | SMN1; SMN2MAPT | |
| SCHEMBL9006000 | 0.67 | TLR8 (0.57) | SMN1; SMN2MAPT | |
| SCHEMBL12277251 | 0.66 | ADORA2A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023230540-A2 | INDAZOLE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| WO-2023230542-A2 | PYRAZOLO[1,5-a]PYRIDINE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| WO-2023230543-A1 | INDOLIZINE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |