Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31252039 | 0.91 | TLR8 (0.43) | TLR8ALDH1A1KMT2APOLBLMNA | |
| SCHEMBL28173216 | 0.81 | KMT2A (0.38) | TLR8ALDH1A1KMT2APOLBLMNA | |
| SCHEMBL10730218 | 0.78 | TLR8 (0.51) | TLR8ALDH1A1KMT2APOLBLMNA | |
| SCHEMBL10730692 | 0.78 | TLR8 (0.51) | TLR8ALDH1A1KMT2APOLBLMNA | |
| SCHEMBL26196835 | 0.77 | KDR (0.32) | TLR8ALDH1A1KMT2APOLBTSHR | |
| SCHEMBL4564156 | 0.76 | TLR8 (0.53) | TLR8ALDH1A1KMT2APOLBLMNA | |
| SCHEMBL3742677 | 0.74 | ALDH1A1 (0.89) | TLR8ALDH1A1KMT2APOLBHTT | |
| SCHEMBL10738786 | 0.73 | ALDH1A1 (0.53) | TLR8ALDH1A1KMT2APOLBLMNA | |
| SCHEMBL15810013 | 0.73 | CA12 (0.33) | TLR8ALDH1A1KMT2APOLBTSHR | |
| SCHEMBL25240227 | 0.73 | ALDH1A1 (0.85) | TLR8ALDH1A1KMT2APOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736013-A1 | N-SUBSTITUTED ARYL TRIFLUOROMETHYL IMIDAZOLES | BAYER AG (DE) | 1996-10-09 | — | — | EP | claimed |
| WO-1995017390-A1 | N-SUBSTITUTED ARYL TRIFLUOROMETHYL IMIDAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-06-29 | — | — | WO | claimed |
| EP-0736013-A1 | N-SUBSTITUTED ARYL TRIFLUOROMETHYL IMIDAZOLES | BAYER AG (DE) | 1996-10-09 | — | — | EP | disclosed |
| EP-0736013-A1 | N-SUBSTITUTED ARYL TRIFLUOROMETHYL IMIDAZOLES | BAYER AG (DE) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017390-A1 | N-SUBSTITUTED ARYL TRIFLUOROMETHYL IMIDAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-06-29 | — | — | WO | disclosed |
| WO-1995017390-A1 | N-SUBSTITUTED ARYL TRIFLUOROMETHYL IMIDAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-06-29 | — | — | WO | disclosed |