SCHEMBL26830774

SCHEMBL26830774

CCCC(NC(=O)NC(CCCCNC(=O)C(C)(C)C)C(=O)O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 18/20 0.57
▸ CPB2 Q96IY4 1/20 0.41
▸ EPHX2 P34913 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23786176 0.87 FOLH1 (0.72) FOLH1
SCHEMBL28670837 0.86 FOLH1 (0.50) FOLH1
SCHEMBL28670835 0.86 FOLH1 (0.50) FOLH1
SCHEMBL13660692 0.80 POLB (0.44) FOLH1
SCHEMBL22950187 0.79 FOLH1 (0.67) FOLH1
SCHEMBL8738364 0.78 FPR2 (0.44) FOLH1
SCHEMBL18538620 0.77 FOLH1 (0.48) FOLH1EPHX2
SCHEMBL23786254 0.77 FOLH1 (0.64) FOLH1
SCHEMBL12216484 0.76 EPHX1 (0.61) FOLH1EPHX2
SCHEMBL13660685 0.75 POLB (0.45) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11827624-B2 Covalent immune recruiter compounds for immune cell recognition and associated uses MCMASTER UNIVERSITY (CA) 2023-11-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11827624-B2 Covalent immune recruiter compounds for immune cell recognition and associated uses CD74, CD4, HLA-A FOLH1 3681/4885CPB2 1867/4885EPHX2 2371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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