Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26832198 | 0.85 | ABCB1 (0.45) | BCHEGAAABCB1TSHR | |
| SCHEMBL26830869 | 0.79 | ABCB1 (0.48) | BCHEGAAABCB1 | |
| SCHEMBL5487793 | 0.74 | ABCB1 (0.44) | BCHEABCB1 | |
| SCHEMBL5487798 | 0.74 | ABCB1 (0.44) | BCHEABCB1 | |
| SCHEMBL14064546 | 0.73 | GAA (0.47) | BCHEGAAABCB1TSHR | |
| SCHEMBL7150067 | 0.72 | PTPN1 (0.56) | BCHE | |
| SCHEMBL7150073 | 0.72 | PTPN1 (0.56) | BCHE | |
| SCHEMBL7153297 | 0.72 | PTPN1 (0.56) | BCHE | |
| SCHEMBL26832050 | 0.72 | BCHE (0.51) | BCHE | |
| SCHEMBL13475155 | 0.72 | BCHE (0.51) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827664-B2 | Biaryl amides with modified sugar groups for treatment of diseases associated with heat shock protein pathway | REATA PHARMACEUTICALS, INC (US) | 2023-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827664-B2 | Biaryl amides with modified sugar groups for treatment of diseases associated with heat shock protein pathway | HSPA2, HSP90AB2P, HSF1 | BCHE 490/4885GAA 315/4885ABCB1 364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.