Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 12/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487798 | 1.00 | ABCB1 (0.44) | ABCB1BCHE | |
| SCHEMBL5492143 | 0.84 | MAPT (0.48) | ABCB1BCHE | |
| SCHEMBL7149873 | 0.84 | ABCB1 (0.43) | ABCB1BCHE | |
| SCHEMBL11398254 | 0.84 | ABCB1 (0.43) | ABCB1BCHE | |
| SCHEMBL5492148 | 0.84 | MAPT (0.48) | ABCB1BCHE | |
| SCHEMBL7152559 | 0.84 | ABCB1 (0.43) | ABCB1BCHE | |
| SCHEMBL26290154 | 0.80 | ABCB1 (0.46) | ABCB1BCHE | |
| SCHEMBL9815624 | 0.80 | LGALS3 (0.44) | ABCB1 | |
| SCHEMBL26830869 | 0.79 | ABCB1 (0.48) | ABCB1BCHE | |
| SCHEMBL9815564 | 0.79 | MAPT (0.41) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644392-B1 | RAPAMYCIN CARBOHYDRATE DERIVATIVES | ISOTECHNIKA INC (CA) | 2007-07-18 | — | — | EP | disclosed |
| EP-1785430-A1 | Rapamycin carbohydrate derivatives | ISOTECHNIKA,INC. (CA) | 2007-05-16 | — | — | EP | disclosed |
| US-20070099848-A1 | Rapamycin carbohydrate derivatives | ISOTECHNIKA INC. (CA) | 2007-05-03 | — | — | US | disclosed |
| US-7160867-B2 | Rapamycin carbohydrate derivatives | ISOTECHNIKA, INC. (CA) | 2007-01-09 | — | — | US | disclosed |
| US-20060079466-A1 | Rapamycin carbohydrate derivatives | ABEL MARK | 2006-04-13 | — | — | US | disclosed |
| EP-1644392-A1 | RAPAMYCIN CARBOHYDRATE DERIVATIVES | ISOTECHNIKA,INC. (CA) | 2006-04-12 | — | — | EP | disclosed |
| US-20040235762-A1 | Rapamycin carbohydrate derivatives | ISOTECHNIKA INC. (CA) | 2004-11-25 | — | — | US | disclosed |
| WO-2004101583-A1 | RAPAMYCIN CARBOHYDRATE DERIVATIVES | ISOTECHNIKA INC. (CA) | 2004-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099848-A1 | Rapamycin carbohydrate derivatives | MTOR, RICTOR, RPTOR | ABCB1 478/4885BCHE 4046/4885 |
| US-20040235762-A1 | Rapamycin carbohydrate derivatives | MTOR, RICTOR, RPTOR | ABCB1 478/4885BCHE 4046/4885 |
| US-20060079466-A1 | Rapamycin carbohydrate derivatives | MTOR, RICTOR, RPTOR | ABCB1 478/4885BCHE 4046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.