Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 16/20 | 0.80 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.53 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26836407 | 0.97 | NAAA (0.81) | NAAATP53MAPTNPC1RAB9A | |
| SCHEMBL26831197 | 0.96 | NAAA (0.80) | NAAATP53MAPTNPC1RAB9A | |
| SCHEMBL26831842 | 0.92 | NAAA (0.71) | NAAATP53MAPTNPC1RAB9A | |
| SCHEMBL30607181 | 0.89 | NAAA (1.00) | NAAATP53MAPT | |
| SCHEMBL19630537 | 0.89 | NAAA (1.00) | NAAATP53MAPT | |
| SCHEMBL21050112 | 0.87 | NAAA (1.00) | NAAATP53MAPT | |
| SCHEMBL30607198 | 0.86 | NAAA (1.00) | NAAATP53MAPT | |
| SCHEMBL19617804 | 0.86 | NAAA (1.00) | NAAATP53MAPT | |
| SCHEMBL19617922 | 0.86 | NAAA (0.81) | NAAA | |
| SCHEMBL30607186 | 0.86 | NAAA (0.81) | NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458447-B1 | PIPERAZINYL METHANONE NAAA INHIBITORS | UNIV CALIFORNIA (US) | 2023-11-29 | — | — | EP | disclosed |