Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 18/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19630537 | 1.00 | NAAA (1.00) | NAAATP53MAPTLMNA | |
| SCHEMBL21050112 | 0.98 | NAAA (1.00) | NAAATP53MAPTLMNA | |
| SCHEMBL19617804 | 0.97 | NAAA (1.00) | NAAATP53MAPTLMNA | |
| SCHEMBL30607198 | 0.97 | NAAA (1.00) | NAAATP53MAPTLMNA | |
| SCHEMBL19630607 | 0.96 | NAAA (1.00) | NAAATP53MAPTLMNA | |
| SCHEMBL30607207 | 0.96 | NAAA (1.00) | NAAATP53MAPTLMNA | |
| SCHEMBL19630612 | 0.92 | NAAA (0.88) | NAAATP53MAPTLMNA | |
| SCHEMBL19630620 | 0.92 | NAAA (0.88) | NAAATP53MAPT | |
| SCHEMBL19630606 | 0.90 | NAAA (1.00) | NAAATP53MAPT | |
| SCHEMBL26835010 | 0.89 | NAAA (0.80) | NAAATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476616-B | Piperazinyl methanone NAAA inhibitors | 加利福尼亚大学董事会 | 2023-10-13 | — | — | CN | disclosed |