Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL564966 | 1.00 | — | — | |
| Alcohol SCHEMBL13730734 | 1.00 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1FFAR3THPO | |
| Alcohol SCHEMBL15987341 | 1.00 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1FFAR3THPO | |
| Alcohol SCHEMBL7606966 | 1.00 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1FFAR3THPO | |
| Alcohol SCHEMBL15823004 | 1.00 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1FFAR3THPO | |
| Alcohol SCHEMBL29169498 | 0.95 | — | — | |
| Alcohol SCHEMBL2347460 | 0.95 | — | — | |
| Alcohol SCHEMBL3199451 | 0.95 | — | — | |
| Alcohol SCHEMBL28056542 | 0.91 | — | — | |
| Acetone SCHEMBL5346221 | 0.88 | ALDH1A1 (0.46) | ALDH1A1TSHRTDP1FFAR3THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7708915-B2 | Polymer microspheres/nanospheres and encapsulating therapeutic proteins therein | APHIOS CORPORATION | 2010-05-04 | — | — | US | claimed |
| US-20100074961-A1 | POLYMER MICROSPHERES/NANOSPHERES AND ENCAPSULATING THERAPEUTIC PROTEINS THEREIN | APHIOS CORPORATION | 2010-03-25 | — | — | US | claimed |
| EP-2699563-B3 | NOVEL PESTICIDAL PYRAZOLE COMPOUNDS | BASF SE (DE) | 2024-06-12 | — | — | EP | disclosed |
| US-9439427-B2 | Pesticidal pyrazole compounds | BASF SE (DE) | 2016-09-13 | — | — | US | disclosed |
| EP-2699563-B1 | NOVEL PESTICIDAL PYRAZOLE COMPOUNDS | BASF SE (DE) | 2016-04-06 | — | — | EP | disclosed |
| US-20160050927-A1 | Novel pesticidal pyrazole compounds | BASF SE (DE) | 2016-02-25 | — | — | US | disclosed |
| US-9198422-B2 | Pesticidal pyrazole compounds | BASF SE (DE) | 2015-12-01 | — | — | US | disclosed |
| EP-2699563-A1 | NOVEL PESTICIDAL PYRAZOLE COMPOUNDS | BASF SE (DE) | 2014-02-26 | — | — | EP | disclosed |
| US-20140045690-A1 | Novel Pesticidal Pyrazole Compounds | BASF SE (DE) | 2014-02-13 | — | — | US | disclosed |
| US-8440614-B2 | Polymer microspheres/nanospheres and encapsulating therapeutic proteins therein | APHIOS CORPORATION (US) | 2013-05-14 | — | — | US | disclosed |
| WO-2012143317-A1 | NOVEL PESTICIDAL PYRAZOLE COMPOUNDS | BASF SE (DE) | 2012-10-26 | — | — | WO | disclosed |
| US-20120114707-A1 | POLYMER MICROSPHERES/NANOSPHERES AND ENCAPSULATING THERAPEUTIC PROTEINS THEREIN | APHIOS CORPORATION | 2012-05-10 | — | — | US | disclosed |
| US-20100233308-A1 | POLYMER MICROSPHERES/NANOSPHERES AND ENCAPSULATING THERAPEUTIC PROTEINS THEREIN | APHIOS CORPORATION | 2010-09-16 | — | — | US | disclosed |
| US-7708915-B2 | Polymer microspheres/nanospheres and encapsulating therapeutic proteins therein | APHIOS CORPORATION | 2010-05-04 | — | — | US | disclosed |
| US-20100074961-A1 | POLYMER MICROSPHERES/NANOSPHERES AND ENCAPSULATING THERAPEUTIC PROTEINS THEREIN | APHIOS CORPORATION | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160050927-A1 | Novel pesticidal pyrazole compounds | CYP51A1, PKM, NOTUM | ALDH1A1 1402/4885TSHR 3627/4885TDP1 1460/4885 |
| US-20140045690-A1 | Novel Pesticidal Pyrazole Compounds | CYP51A1, PKM, NOTUM | ALDH1A1 1402/4885TSHR 3627/4885TDP1 1460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.