Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19402915 | 0.80 | MAP4K4 (0.41) | — | |
| SCHEMBL17175156 | 0.76 | EGFR (0.45) | ALDH1A1EGLN2EGFRKDR | |
| SCHEMBL17253542 | 0.73 | EGFR (0.35) | KMT2AALDH1A1EGLN2EGFRKDR | |
| SCHEMBL6844956 | 0.73 | CHRNA7 (0.34) | ALDH1A1EGLN2EGFRKDR | |
| SCHEMBL8001535 | 0.73 | ALDH1A1 (0.32) | ALDH1A1EGLN2EGFRKDR | |
| SCHEMBL17175025 | 0.70 | ALDH1A1 (0.33) | MEN1KMT2AALDH1A1EGLN2EGFR | |
| SCHEMBL20276953 | 0.69 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL13412188 | 0.68 | EGLN2 (0.49) | EGLN2 | |
| SCHEMBL6370757 | 0.68 | ALDH1A1 (0.45) | ALDH1A1EGLN2 | |
| SCHEMBL12173502 | 0.67 | MAP4K4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365546-A1 | 5-SUBSTITUTED INDOLE 3-AMIDE DERIVATIVES, PREPARATION METHOD AND USE THEREOF | ORIGIANT PHARMACEUTICAL CO., LTD (CN) | 2023-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365546-A1 | 5-SUBSTITUTED INDOLE 3-AMIDE DERIVATIVES, PREPARATION METHOD AND USE THEREOF | RIPK1, RIPK3, RIPK2 | MEN1 1745/4885KMT2A 2607/4885ALDH1A1 3976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.