Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 10/20 | 0.59 |
| ▸ | PRNP | P04156 | 5/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24087965 | 0.92 | ACMSD (0.70) | ACMSDPRNPRXFP1MEN1KMT2A | |
| SCHEMBL26847283 | 0.87 | PRNP (0.53) | ACMSDPRNPRXFP1MEN1KMT2A | |
| SCHEMBL24087878 | 0.86 | ACMSD (0.70) | ACMSDPRNPRXFP1MEN1KMT2A | |
| SCHEMBL24088170 | 0.83 | ACMSD (0.55) | ACMSDPRNPRXFP1MEN1KMT2A | |
| SCHEMBL26847147 | 0.83 | ACMSD (0.85) | ACMSDPRNPRXFP1MEN1KMT2A | |
| SCHEMBL24087912 | 0.79 | ACMSD (0.48) | ACMSDPRNPRXFP1MEN1KMT2A | |
| SCHEMBL26847281 | 0.79 | ACMSD (0.47) | ACMSDPRNPRXFP1MEN1KMT2A | |
| SCHEMBL24087921 | 0.79 | ACMSD (0.54) | ACMSDPRNPRXFP1MEN1KMT2A | |
| SCHEMBL26847267 | 0.79 | ACMSD (0.52) | ACMSDPRNPRXFP1MEN1KMT2A | |
| SCHEMBL26847495 | 0.78 | ACMSD (0.56) | ACMSDPRNPRXFP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381177-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | TES PHARMA S.R.L. (IT) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381177-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | ACMSD, GLS, ALDH7A1 | ACMSD 1/4885PRNP 569/4885RXFP1 4311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.