Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 9/20 | 0.33 |
| ▸ | POLB | P06746 | 6/20 | 0.33 |
| ▸ | TNF | P01375 | 2/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26847367 | 0.90 | KMT2A (0.40) | HSD11B1ACMSDKMT2AHPGDALDH1A1 | |
| SCHEMBL26847371 | 0.88 | KDM4E (0.39) | ACMSDKMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL26847313 | 0.83 | ACMSD (0.32) | ACMSDKMT2AMEN1POLBCYP2C19 | |
| SCHEMBL26847307 | 0.81 | KMT2A (0.39) | HSD11B1ACMSDKMT2AHPGDALDH1A1 | |
| SCHEMBL24087895 | 0.79 | ACMSD (0.45) | HSD11B1ACMSDKMT2AHPGDALDH1A1 | |
| SCHEMBL26847363 | 0.79 | ACMSD (0.45) | ACMSDKMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL20340157 | 0.78 | ACMSD (0.51) | HSD11B1ACMSDKMT2AHPGDALDH1A1 | |
| SCHEMBL31443033 | 0.78 | ACMSD (0.51) | HSD11B1ACMSDKMT2AHPGDALDH1A1 | |
| SCHEMBL20339841 | 0.76 | KMT2A (0.54) | ACMSDKMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL26847309 | 0.74 | ACMSD (0.39) | HSD11B1ACMSDKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381177-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | TES PHARMA S.R.L. (IT) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381177-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | ACMSD, GLS, ALDH7A1 | HSD11B1 1734/4885ACMSD 1/4885KMT2A 1353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.