Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | PRNP | P04156 | 5/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26847351 | 0.84 | KDM4E (0.45) | NPSR1MEN1KMT2APRNPRXFP1 | |
| SCHEMBL24088138 | 0.81 | RXFP1 (0.41) | NPSR1MEN1KMT2APRNPRXFP1 | |
| SCHEMBL24087933 | 0.76 | NPSR1 (0.44) | NPSR1MEN1KMT2APRNPRXFP1 | |
| SCHEMBL26847372 | 0.74 | SERPINH1 (0.43) | NPSR1MEN1KMT2APRNPRXFP1 | |
| SCHEMBL24087883 | 0.74 | MEN1 (0.43) | NPSR1MEN1KMT2APRNPRXFP1 | |
| SCHEMBL24087884 | 0.74 | ACMSD (0.44) | NPSR1MEN1KMT2APRNPRXFP1 | |
| SCHEMBL26847375 | 0.74 | KDM4E (0.44) | NPSR1MEN1KMT2APRNPRXFP1 | |
| SCHEMBL24087888 | 0.73 | RXFP1 (0.50) | NPSR1MEN1KMT2APRNPRXFP1 | |
| SCHEMBL23850227 | 0.73 | ACMSD (0.68) | NPSR1MEN1KMT2APRNPRXFP1 | |
| SCHEMBL26847386 | 0.72 | ACMSD (0.46) | NPSR1MEN1KMT2APRNPRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381177-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | TES PHARMA S.R.L. (IT) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381177-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | ACMSD, GLS, ALDH7A1 | NPSR1 2669/4885MEN1 2572/4885KMT2A 1353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.