Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2685255 | 0.79 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL30108090 | 0.79 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9302774 | 0.77 | ALOX5 (0.62) | ALOX5 | |
| SCHEMBL9009080 | 0.74 | ALOX5 (0.66) | ALOX5 | |
| SCHEMBL9008940 | 0.74 | ALOX5 (0.63) | ALOX5 | |
| SCHEMBL9300351 | 0.74 | ALOX5 (0.61) | ALOX5 | |
| SCHEMBL7809023 | 0.73 | ALOX5 (0.64) | ALOX5 | |
| SCHEMBL13920494 | 0.72 | ALOX5 (0.87) | ALOX5 | |
| SCHEMBL9009119 | 0.72 | ALOX5 (0.63) | ALOX5 | |
| SCHEMBL9302861 | 0.71 | ALOX5 (0.62) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8669289-B2 | Methods and compositions relating to hematologic malignancies | THE JACKSON LABORATORY (US) | 2014-03-11 | — | — | US | disclosed |
| US-20120114605-A1 | METHODS AND COMPOSITIONS RELATING TO HEMATOLOGIC MALIGNANCIES | THE JACKSON LABORATORY | 2012-05-10 | — | — | US | disclosed |
| WO-2010124283-A2 | METHODS AND COMPOSITIONS RELATING TO HEMATOLOGIC MALIGNANCIES | THE JACKSON LABORATORY (US) | 2010-10-28 | — | — | WO | disclosed |