Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 17/20 | 0.63 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9009080 | 0.92 | ALOX5 (0.66) | ALOX5GPR84 | |
| SCHEMBL9008940 | 0.91 | ALOX5 (0.63) | ALOX5GPR84 | |
| SCHEMBL7809023 | 0.80 | ALOX5 (0.64) | ALOX5 | |
| SCHEMBL9302774 | 0.77 | ALOX5 (0.62) | ALOX5 | |
| SCHEMBL9009008 | 0.74 | ALOX5 (0.67) | ALOX5 | |
| SCHEMBL2685255 | 0.73 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL30108090 | 0.73 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL2685256 | 0.72 | ALOX5 (0.66) | ALOX5 | |
| SCHEMBL8474402 | 0.71 | ALOX5 (0.57) | ALOX5 | |
| SCHEMBL9009118 | 0.69 | ALOX5 (0.42) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576338-A | ANTIALLERGENS, ANTIHISTAMINES, ANTIINFLAMMATORY AGENTS AND CYTOPROTECTIVE AGENTS FOR CARDIOVASCULAR DISORDERS | MERCK FROSST CANADA, INC. (CA) | 1996-11-19 | — | — | US | disclosed |