Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 13/20 | 0.45 |
| ▸ | TDO2 | P48775 | 10/20 | 0.44 |
| ▸ | IDO2 | Q6ZQW0 | 9/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26860827 | 0.83 | TDO2 (0.62) | APAF1IDO1TDO2IDO2KMT2A | |
| SCHEMBL26614209 | 0.83 | APAF1 (0.63) | APAF1IDO1TDO2IDO2KMT2A | |
| SCHEMBL26856391 | 0.80 | IDO1 (0.52) | APAF1IDO1TDO2IDO2KMT2A | |
| SCHEMBL26855996 | 0.80 | APAF1 (0.50) | APAF1IDO1TDO2IDO2KMT2A | |
| SCHEMBL30639058 | 0.80 | APAF1 (0.53) | APAF1IDO1TDO2IDO2KMT2A | |
| SCHEMBL26614131 | 0.80 | APAF1 (0.53) | APAF1IDO1TDO2IDO2KMT2A | |
| SCHEMBL31382877 | 0.79 | TDO2 (0.69) | APAF1IDO1TDO2IDO2KMT2A | |
| SCHEMBL31382846 | 0.79 | CHEK1 (0.67) | APAF1IDO1TDO2IDO2KMT2A | |
| SCHEMBL31382855 | 0.79 | APAF1 (0.49) | APAF1IDO1TDO2IDO2KMT2A | |
| SCHEMBL26614226 | 0.79 | APAF1 (0.49) | APAF1IDO1TDO2IDO2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |