Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 4/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16704791 | 0.93 | CHRM2 (0.50) | ALDH1A1TSHRMAPK1SMN1; SMN2CHRM2 | |
| SCHEMBL1563851 | 0.93 | CHRM2 (0.50) | ALDH1A1TSHRMAPK1SMN1; SMN2CHRM2 | |
| SCHEMBL30341 | 0.92 | — | — | |
| SCHEMBL334658 | 0.92 | — | — | |
| SCHEMBL334659 | 0.92 | — | — | |
| Methane SCHEMBL11336685 | 0.89 | — | — | |
| SCHEMBL16809957 | 0.89 | ALDH1A1 (0.50) | ALDH1A1TSHRMAPK1SMN1; SMN2CHRM2 | |
| Propane SCHEMBL22090164 | 0.86 | — | — | |
| SCHEMBL3660412 | 0.86 | ALDH1A1 (0.48) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| Cyclohexane SCHEMBL663995 | 0.86 | ALDH1A1 (0.48) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9994443-B2 | Modified nicotinic compounds and related methods | SELECTA BIOSCIENCES, INC. (US) | 2018-06-12 | — | — | US | disclosed |
| EP-2640190-A1 | MODIFIED NICOTINIC COMPOUNDS AND RELATED METHODS | Selecta Biosciences, Inc. (US) | 2013-09-25 | — | — | EP | disclosed |
| WO-2012061717-A1 | MODIFIED NICOTINIC COMPOUNDS AND RELATED METHODS | SELECTA BIOSCIENCES, INC. (US) | 2012-05-10 | — | — | WO | disclosed |
| US-20120114677-A1 | MODIFIED NICOTINIC COMPOUNDS AND RELATED METHODS | SELECTA BIOSCIENCES, INC. (US) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120114677-A1 | MODIFIED NICOTINIC COMPOUNDS AND RELATED METHODS | NNMT, CHRNG, CHRM5 | ALDH1A1 1321/4885TSHR 2185/4885MAPK1 4641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.