Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 4/20 | 0.36 |
| ▸ | TDO2 | P48775 | 3/20 | 0.36 |
| ▸ | IDO2 | Q6ZQW0 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26864086 | 1.00 | TDP2 (0.36) | TDP2IDO1TDO2IDO2MEN1 | |
| SCHEMBL26614267 | 0.90 | IDO1 (0.44) | IDO1TDO2IDO2MEN1KMT2A | |
| SCHEMBL26614215 | 0.89 | IDO1 (0.42) | TDP2IDO1TDO2IDO2MEN1 | |
| SCHEMBL30639114 | 0.89 | IDO1 (0.42) | TDP2IDO1TDO2IDO2MEN1 | |
| SCHEMBL30639067 | 0.88 | IDO1 (0.47) | IDO1TDO2IDO2MEN1KMT2A | |
| SCHEMBL26614101 | 0.88 | IDO1 (0.47) | IDO1TDO2IDO2MEN1KMT2A | |
| SCHEMBL26614116 | 0.79 | IDO1 (0.48) | IDO1TDO2IDO2MEN1KMT2A | |
| SCHEMBL26855338 | 0.78 | IDO1 (0.47) | TDP2IDO1TDO2IDO2MEN1 | |
| SCHEMBL26614249 | 0.77 | IDO1 (0.60) | IDO1TDO2IDO2MEN1KMT2A | |
| SCHEMBL26614138 | 0.74 | IDO1 (0.55) | IDO1TDO2IDO2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |