Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 13/20 | 0.47 |
| ▸ | TDO2 | P48775 | 11/20 | 0.47 |
| ▸ | IDO2 | Q6ZQW0 | 8/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26855991 | 0.88 | KMT2A (0.54) | IDO1TDO2IDO2KMT2AMEN1 | |
| SCHEMBL31382838 | 0.86 | IDO1 (0.63) | IDO1TDO2IDO2KMT2AMEN1 | |
| SCHEMBL26614193 | 0.86 | IDO1 (0.63) | IDO1TDO2IDO2KMT2AMEN1 | |
| SCHEMBL26855601 | 0.80 | IDO1 (0.48) | IDO1TDO2IDO2KMT2AMEN1 | |
| SCHEMBL26857749 | 0.78 | TDP2 (0.36) | IDO1TDO2IDO2KMT2AMEN1 | |
| SCHEMBL26864086 | 0.78 | TDP2 (0.36) | IDO1TDO2IDO2KMT2AMEN1 | |
| SCHEMBL26614256 | 0.75 | IDO1 (0.77) | IDO1TDO2IDO2KMT2AMEN1 | |
| SCHEMBL26855331 | 0.75 | KMT2A (0.49) | IDO1TDO2IDO2KMT2AMEN1 | |
| SCHEMBL4585634 | 0.73 | IDO1 (0.80) | IDO1TDO2IDO2KMT2AMEN1 | |
| SCHEMBL26614209 | 0.73 | APAF1 (0.63) | IDO1TDO2IDO2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |