SCHEMBL26862

SCHEMBL26862

COc1ccc(C(Cl)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.54
LTA4H P09960 2/20 0.52
KIF11 P52732 8/20 0.51
KCNH2 Q12809 1/20 0.51
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
TRPA1 O75762 1/20 0.47
ALDH1A1 P00352 2/20 0.45
TSHR P16473 1/20 0.45
MAPK1 P28482 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
LMNA P02545 1/20 0.44
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CES2 O00748 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL121800 1.00 CA4 (0.54) CA4LTA4HKIF11KCNH2CA12
SCHEMBL16698731 1.00 CA4 (0.54) CA4LTA4HKIF11KCNH2CA12
SCHEMBL21551879 0.98 CA4 (0.52) CA4LTA4HKIF11KCNH2CA12
Ammonia Solution, Strong SCHEMBL17187816 0.98 CA4 (0.52) CA4LTA4HKIF11KCNH2CA12
SCHEMBL12730666 0.92 ACHE (0.56) CA4LTA4HKIF11KCNH2CA12
SCHEMBL16321127 0.92 ACHE (0.56) CA4LTA4HKIF11KCNH2CA12
SCHEMBL1975657 0.91 CA1 (0.58) CA4LTA4HCA12CA1CA2
SCHEMBL31123784 0.89 CA4 (0.48) CA4LTA4HKIF11KCNH2CA1
SCHEMBL21682186 0.89 CA4 (0.48) CA4LTA4HKIF11KCNH2CA1
Pyridine SCHEMBL2907844 0.89 AHR (0.47) CA4LTA4HKIF11KCNH2TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9108 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122011024-A Phosphoramidite monomer containing bio-orthogonal groups and preparation method and application thereof 沈阳药科大学 2026-05-12 CN claimed
CN-122011035-A Asymmetric catalytic synthesis of pentavalent oxygen sulphur phosphane monomer and preparation method of intermediate thereof 上海交通大学 2026-05-12 CN claimed
US-20250368998-A1 NUCLEOTIDE ANALOGUES, AND PREPARATION AND APPLICATION THEREOF HITGEN INC (CN) 2025-12-04 US claimed
EP-4640687-A1 LINKER FOR NUCLEIC ACID SYNTHESIS, CARRIER, AND METHODS FOR PRODUCING SAME SynCrest Inc. (JP) 2025-10-29 EP claimed
US-20250236633-A1 SYNTHESIS OF ISOMERICALLY PURE POLYOL-BASED PHOSPHORAMIDITES Roche Sequencing Solutions, Inc. (US) 2025-07-24 US claimed
CN-120157726-A Preparation method of 2' -alkoxyuridine derivative 芜湖华仁科技有限公司 2025-06-17 CN claimed
CN-120025373-A Preparation of 2' -OMe modified pseudouridine and N1-methyl pseudouridine phosphoramidite monomers 武汉糖智药业有限公司 2025-05-23 CN claimed
CN-119241622-B 3′-ONH2Synthesis method of ribonucleotide 凯莱英生命科学技术(天津)有限公司 2025-04-18 CN claimed
CN-119823204-A Synthesis and application of N-acetyl protected guanosine RNA monomer 苏州锦博莱生物医药科技有限公司 2025-04-15 CN claimed
CN-119564873-A Aptamer probe for targeting EpCAM and preparation method and application thereof 四川迪亚生物科技集团有限公司 2025-03-07 CN claimed
US-5631360-A MULTISTAGE SYNTHESIS, TREATMENT OF NUCLEOSIDES, ADDING A N-PHTHALOYL GROUP, DEPROTECTING THE HYDROXY, TRITYLATION AND PHOSPHITYLATION RIBOZYME PHARMACEUTICALS, INC. (US) 1997-05-20 US claimed
EP-0755939-A2 Method for the targetted synthesis of beta-glycoside bound N-acetyl glucosamine derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1997-01-29 EP claimed
US-5567811-A Phosphoramidite derivatives, their preparation and the use thereof in the incorporation of reporter groups on synthetic oligonucleotides AMERSHAM INTERNATIONAL PLC (GB) 1996-10-22 US claimed
WO-1996016077-A2 REAGENT FOR QUANTIFYING FREE AMINE GROUPS AGOURON PHARMACEUTICALS, INC. (US) 1996-05-30 WO claimed
EP-0527184-B1 PHOSPHORAMIDITE DERIVATIVES, THEIR PREPARATION AND THE USE THEREOF IN THE INCORPORATION OF REPORTER GROUPS ON SYNTHETIC OLIGONUCLEOTIDES AMERSHAM INT PLC (GB) 1995-08-02 EP claimed
US-5198540-A Sequential linking of nucleotides to a carrier molecule, releasing, chromatographic separation PERSEPTIVE BIOSYSTEMS, INC. 1993-03-30 US claimed
EP-0527184-A1 PHOSPHORAMIDITE DERIVATIVES, THEIR PREPARATION AND THE USE THEREOF IN THE INCORPORATION OF REPORTER GROUPS ON SYNTHETIC OLIGONUCLEOTIDES. AMERSHAM INT PLC (GB) 1993-02-17 EP claimed
WO-1991017169-A1 PHOSPHORAMIDITE DERIVATIVES, THEIR PREPARATION AND THE USE THEREOF IN THE INCORPORATION OF REPORTER GROUPS ON SYNTHETIC OLIGONUCLEOTIDES AMERSHAM INTERNATIONAL PLC (GB) 1991-11-14 WO claimed
US-4837312-A Chelator-functionalized nucleosides and nucleotides and methods for making same CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1989-06-06 US claimed
US-4800166-A TRITYL HALIDE OR CARVOXYLATE TO BIND WITH FREE AMINO GROUPS APPLIED PROTEIN TECHNOLOGIES, INC. (US) 1989-01-24 US claimed