SCHEMBL31123784

SCHEMBL31123784

COc1ccc(C(Cl)(c2ccccc2)c2cccc(OC)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.48
LTA4H P09960 1/20 0.47
KIF11 P52732 3/20 0.47
KCNH2 Q12809 1/20 0.44
RELA Q04206 1/20 0.42
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
ACHE P22303 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2A6 P11509 1/20 0.41
MAOB P27338 1/20 0.41
ENPP2 Q13822 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
ALDH1A1 P00352 3/20 0.40
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21682186 1.00 CA4 (0.48) CA4LTA4HKIF11KCNH2RELA
SCHEMBL794410 0.95 KIF11 (0.50) CA4LTA4HKIF11NPC1RAB9A
SCHEMBL13061830 0.90 LTA4H (0.47) CA4LTA4HKIF11KCNH2RELA
SCHEMBL26862 0.89 CA4 (0.54) CA4LTA4HKIF11KCNH2SIGMAR1
SCHEMBL16698731 0.89 CA4 (0.54) CA4LTA4HKIF11KCNH2SIGMAR1
SCHEMBL121800 0.89 CA4 (0.54) CA4LTA4HKIF11KCNH2SIGMAR1
SCHEMBL21551879 0.87 CA4 (0.52) CA4LTA4HKIF11KCNH2SIGMAR1
Methane SCHEMBL28252951 0.87 CA4 (0.52) CA4LTA4HKIF11KCNH2SIGMAR1
Ammonia Solution, Strong SCHEMBL17187816 0.87 CA4 (0.52) CA4LTA4HKIF11KCNH2SIGMAR1
SCHEMBL13939468 0.84 ACHE (0.46) LTA4HKIF11RELARAB9AACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112805006-B PRMT5 inhibitors 默沙东有限责任公司 2024-09-24 CN disclosed