Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 14/20 | 0.72 |
| ▸ | KDM5C | P41229 | 8/20 | 0.72 |
| ▸ | KDM5A | P29375 | 7/20 | 0.72 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.72 |
| ▸ | KDM4A | O75164 | 2/20 | 0.57 |
| ▸ | KDM6B | O15054 | 1/20 | 0.57 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.57 |
| ▸ | KDM5D | Q9BY66 | 1/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | JMJD6 | Q6NYC1 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29373338 | 0.84 | KDM5B (1.00) | KDM5BKDM5CKDM5AKDM4CKDM4A | |
| SCHEMBL15637431 | 0.84 | KDM5B (1.00) | KDM5BKDM5CKDM5AKDM4CKDM4A | |
| SCHEMBL21716674 | 0.84 | KDM5B (0.73) | KDM5BKDM5CKDM5AKDM4CKDM4A | |
| SCHEMBL21716673 | 0.80 | KDM5B (0.82) | KDM5BKDM5CKDM5AKDM4CKDM4A | |
| SCHEMBL19676470 | 0.78 | KDM5B (0.86) | KDM5BKDM5CKDM5AKDM4CKDM4A | |
| SCHEMBL15637682 | 0.78 | KDM5B (0.86) | KDM5BKDM5CKDM5AKDM4CKDM4A | |
| SCHEMBL16291430 | 0.77 | KDM5B (0.83) | KDM5BKDM5CKDM5AKDM4CKDM4A | |
| SCHEMBL18708524 | 0.77 | KDM5B (0.83) | KDM5BKDM5CKDM5AKDM4CKDM4A | |
| SCHEMBL15994246 | 0.76 | KDM5B (0.76) | KDM5BKDM5CKDM5AKDM4CKDM4A | |
| SCHEMBL15637410 | 0.76 | KDM5B (0.81) | KDM5BKDM5CKDM5AKDM4CKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382865-A1 | HISTONE DEMETHYLASE 5 INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382865-A1 | HISTONE DEMETHYLASE 5 INHIBITORS AND USES THEREOF | KDM5A, KDM5B, KDM5C | KDM5B 2/4885KDM5C 3/4885KDM5A 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.