SCHEMBL29373338

SCHEMBL29373338

CCOC(=O)c1ccnc(CNCC(=O)N(CC)CCN(C)C)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ KDM5B Q9UGL1 14/20 1.00
▸ KDM5C P41229 8/20 1.00
▸ KDM5A P29375 7/20 1.00
▸ KDM4C Q9H3R0 2/20 1.00
▸ KDM4A O75164 2/20 0.78
▸ KDM6B O15054 1/20 0.78
▸ KDM2B Q8NHM5 1/20 0.78
▸ KDM5D Q9BY66 1/20 0.77
▸ JMJD6 Q6NYC1 3/20 0.41
▸ PIK3CA P42336 1/20 0.39
▸ NPC1 O15118 1/20 0.39
▸ TP53 P04637 1/20 0.39
▸ POLB P06746 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15637431 1.00 KDM5B (1.00) KDM5BKDM5CKDM5AKDM4CKDM4A
SCHEMBL19676470 0.93 KDM5B (0.86) KDM5BKDM5CKDM5AKDM4CKDM4A
SCHEMBL15637682 0.92 KDM5B (0.86) KDM5BKDM5CKDM5AKDM4CKDM4A
SCHEMBL18708524 0.91 KDM5B (0.83) KDM5BKDM5CKDM5AKDM4CKDM4A
SCHEMBL16291430 0.91 KDM5B (0.83) KDM5BKDM5CKDM5AKDM4CKDM4A
SCHEMBL21716673 0.90 KDM5B (0.82) KDM5BKDM5CKDM5AKDM4CKDM4A
SCHEMBL15637410 0.90 KDM5B (0.81) KDM5BKDM5CKDM5AKDM4CKDM4A
SCHEMBL16291798 0.90 KDM5B (0.81) KDM5BKDM5CKDM5AKDM4CKDM4A
SCHEMBL19676368 0.89 KDM5B (0.80) KDM5BKDM5CKDM5AKDM4CKDM4A
SCHEMBL18286846 0.89 KDM5B (0.80) KDM5BKDM5CKDM5AKDM4CKDM4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120137885-A Culture solution additive for improving embryo development potential and application thereof 山东大学 2025-06-13 — — CN claimed
EP-4058604-B1 COMPOSITIONS AND METHODS FOR REGULATING EGFR AMPLIFICATION IN CANCER CELLS FOR IMPROVING EGFR-TARGETED ANTI-CANCER AGENT INSTITUTE FOR CANCER RES (US) 2026-04-22 — — EP disclosed
EP-3692152-B1 METHODS AND COMPOSITIONS FOR ALTERING FUNCTION AND STRUCTURE OF CHROMATIN LOOPS AND/OR DOMAINS BROAD INST INC (US) 2025-09-03 — — EP disclosed
US-20250215486-A1 LIVER PROTECTIVE MARC VARIANTS AND USES THEREOF THE GENERAL HOSPITAL CORPORATION (US) 2025-07-03 — — US disclosed
CN-120137885-A Culture solution additive for improving embryo development potential and application thereof 山东大学 2025-06-13 — — CN disclosed
WO-2025085311-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF KMT2D-DEFICIENT CANCERS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-04-24 — — WO disclosed
EP-3962559-B1 METHODS AND COMPOSITIONS FOR TREATING CHRONIC INFLAMMATORY INJURY, METAPLASIA, DYSPLASIA AND CANCERS OF EPITHELIAL TISSUES UNIV HOUSTON SYSTEM (US) 2025-04-16 — — EP disclosed
EP-4529468-A1 FORMULATION OF API'S AND EXCIPIENT'S IN AN ICELL VIA HYDROPHOBIC ION PAIRING Danmarks Tekniske Universitet (DK) 2025-04-02 — — EP disclosed
EP-4529477-A1 POROUS EXPANDING BIOCOMPATIBLE SCAFFOLDS Danmarks Tekniske Universitet (DK) 2025-04-02 — — EP disclosed
US-12215382-B2 Liver protective MARC variants and uses thereof THE GENERAL HOSPITAL CORPORATION (US) 2025-02-04 — — US disclosed
US-20220339285-A1 DISSACHARIDE FORMULATIONS FOR CONTROLLED DRUG RELEASE TECHNICAL UNIVERSITY OF DENMARK (DK) 2022-10-27 — — US disclosed
EP-4058604-A1 COMPOSITIONS AND METHODS FOR REGULATING EGFR AMPLIFICATION IN CANCER CELLS FOR IMPROVING EGFR-TARGETED ANTI-CANCER AGENT Institute For Cancer Research d/b/a The Research Institute of Fox Chase Cancer Center (US) 2022-09-21 — — EP disclosed
US-20220202792-A1 METHODS AND COMPOSITIONS FOR TREATING CHRONIC INFLAMMATORY INJURY, METAPLASIA, DYSPLASIA AND CANCERS OF EPITHELIAL TISSUES UNIVERSITY OF HOUSTON SYSTEM (US) 2022-06-30 — — US disclosed
US-20220192984-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING OTIC THERAPEUTIC AGENTS AND RELATED METHODS Frequency Therapeutics, Inc. 2022-06-23 — — US disclosed
US-20220160664-A1 TAZ ACTIVATORS AND WNT AGONISTS FOR TREATING EAR DISORDERS UNITED STATES GOVERNMENT 2022-05-26 — — US disclosed
CN-113663076-B Cancer combination therapy composition 厦门大学 2022-05-13 — — CN disclosed
US-20220127568-A1 COMPOSITIONS AND METHODS FOR GENERATING HAIR CELLS BY INHIBITING EPIGENETIC TARGETS Frequency Therapeutics, Inc. (US) 2022-04-28 — — US disclosed
EP-3982922-A1 DISSACHARIDE FORMULATIONS FOR CONTROLLED DRUG RELEASE Technical University of Denmark (DK) 2022-04-20 — — EP disclosed
EP-3962559-A1 METHODS AND COMPOSITIONS FOR TREATING CHRONIC INFLAMMATORY INJURY, METAPLASIA, DYSPLASIA AND CANCERS OF EPITHELIAL TISSUES University of Houston System (US) 2022-03-09 — — EP disclosed
CN-114007671-A Methods and compositions for treating chronic inflammatory injury, metaplasia, dysplasia and cancer of epithelial tissue 休斯敦大学体系 2022-02-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220127568-A1 COMPOSITIONS AND METHODS FOR GENERATING HAIR CELLS BY INHIBITING EPIGENETIC TARGETS WNT3A, WNT1, MECP2 KDM5B 344/4885KDM5C 243/4885KDM5A 291/4885
US-20220202792-A1 METHODS AND COMPOSITIONS FOR TREATING CHRONIC INFLAMMATORY INJURY, METAPLASIA, DYSPLASIA AND CANCERS OF EPITHELIAL TISSUES FABP2, MUC1, FABP6 KDM5B 4202/4885KDM5C 3315/4885KDM5A 4362/4885
US-20220339285-A1 DISSACHARIDE FORMULATIONS FOR CONTROLLED DRUG RELEASE LIPA, LIPE, CEL KDM5B 1918/4885KDM5C 1839/4885KDM5A 2149/4885
US-20220160664-A1 TAZ ACTIVATORS AND WNT AGONISTS FOR TREATING EAR DISORDERS WNT1, WNT3A, CTNNB1 KDM5B 4472/4885KDM5C 4439/4885KDM5A 4354/4885
US-20220192984-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING OTIC THERAPEUTIC AGENTS AND RELATED METHODS OTC, EXOSC5, ENTPD5 KDM5B 4560/4885KDM5C 4362/4885KDM5A 4642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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