Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8177411 | 1.00 | LMNA (0.31) | LMNA | |
| SCHEMBL3625420 | 0.98 | — | — | |
| SCHEMBL8764846 | 0.76 | LMNA (0.31) | LMNA | |
| SCHEMBL18984959 | 0.76 | THRB (0.31) | LMNA | |
| SCHEMBL7641162 | 0.76 | LMNA (0.42) | LMNA | |
| SCHEMBL7643011 | 0.76 | LMNA (0.42) | LMNA | |
| SCHEMBL16054171 | 0.76 | — | — | |
| SCHEMBL27096230 | 0.76 | — | — | |
| SCHEMBL21611858 | 0.73 | — | — | |
| SCHEMBL6933252 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120114544-A1 | ORGANIC CHLOROHYDROSILANE AND METHOD FOR PREPARING THEM | SAMSUNG FINE CHEMICALS CO., LTD (KR) | 2012-05-10 | — | — | US | disclosed |
| CN-102419497-A | Method for producing liquid crystal alignment film and retardation film, liquid crystal alignment agent, liquid crystal alignment film, and retardation film | JSR KK | 2012-04-18 | — | — | CN | disclosed |
| CN-102337140-A | Liquid crystal aligning agent for retardation film, liquid crystal alignment film for retardation film, and retardation film and process for production thereof | JSR CORP | 2012-02-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120114544-A1 | ORGANIC CHLOROHYDROSILANE AND METHOD FOR PREPARING THEM | PHPT1, SIK1, SIK2 | LMNA 4399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.