Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 11/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26868111 | 0.81 | PIM1 (0.36) | TYK2KDM4ENPC1RAB9AMAPT | |
| SCHEMBL26869154 | 0.77 | KDM4E (0.34) | TYK2PDE4DKDM4ENPC1RAB9A | |
| SCHEMBL26872817 | 0.76 | RAB9A (0.46) | KDM4ENPC1RAB9AMAPTATM | |
| SCHEMBL26875254 | 0.74 | CDK2 (0.37) | TYK2PDE4DKDM4ENPC1RAB9A | |
| SCHEMBL26253982 | 0.74 | TYK2 (0.45) | TYK2KDM4ENPC1RAB9AMAPT | |
| SCHEMBL26869324 | 0.72 | TYK2 (0.36) | TYK2PDE4DKDM4ENPC1RAB9A | |
| SCHEMBL23772369 | 0.71 | CDK2 (0.46) | TYK2PDE4DKDM4ERAB9AMAPT | |
| SCHEMBL26868144 | 0.71 | CCNT1 (0.39) | TYK2PDE4DKDM4EHTTCDK2 | |
| SCHEMBL26873337 | 0.71 | CDK2 (0.39) | TYK2PDE4DKDM4ENPC1RAB9A | |
| SCHEMBL26871074 | 0.70 | KDM4E (0.35) | KDM4ERAB9AMAPTHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282868-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-11-29 | — | — | EP | disclosed |