Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 3/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
| ▸ | CHUK | O15111 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26871792 | 0.83 | CSNK2B (0.46) | KDM4EMAPTNPC1RAB9AATM | |
| SCHEMBL26870979 | 0.81 | KDM4E (0.36) | KDM4EMAPTRAB9A | |
| SCHEMBL26869184 | 0.81 | KDM4E (0.36) | KDM4EMAPTNPC1RAB9ACDK2 | |
| SCHEMBL26871796 | 0.78 | CDK9 (0.48) | CDK2 | |
| SCHEMBL26868079 | 0.77 | TYK2 (0.36) | KDM4EMAPTNPC1RAB9AATM | |
| SCHEMBL26253982 | 0.75 | TYK2 (0.45) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL23772369 | 0.72 | CDK2 (0.46) | KDM4EMAPTRAB9ACDK2TYK2 | |
| SCHEMBL26873603 | 0.69 | CSNK2B (0.46) | KDM4EMAPTNPC1RAB9AATM | |
| SCHEMBL26871218 | 0.68 | KDM4E (0.34) | KDM4EMAPTRAB9ACDK2 | |
| SCHEMBL26871243 | 0.66 | KDM4E (0.33) | KDM4EMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282868-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-11-29 | — | — | EP | disclosed |