SCHEMBL268688

SCHEMBL268688

c1ccc(CC2(Cc3ccccc3)CCCCCCC2)cc1

nearest known ligand 0.63

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.52
MAOB P27338 1/20 0.52
OPRM1 P35372 3/20 0.43
OPRL1 P41146 3/20 0.43
GAA P10253 1/20 0.42
ALDH1A1 P00352 2/20 0.41
ADRB2 P07550 2/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
POLB P06746 1/20 0.39
OPRK1 P41145 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4581280 1.00 MAOA (0.52) MAOAMAOBOPRM1OPRL1GAA
SCHEMBL1588016 1.00 MAOA (0.52) MAOAMAOBOPRM1OPRL1GAA
SCHEMBL8347115 0.98 MAOA (0.54) MAOAMAOBOPRM1OPRL1GAA
SCHEMBL156160 0.93 MAOA (0.54) MAOAMAOBOPRM1OPRL1GAA
Formamide SCHEMBL28694742 0.88 MAOA (0.47) MAOAMAOBOPRM1OPRL1GAA
SCHEMBL2864890 0.87 MAOA (0.50) MAOAMAOBOPRM1OPRL1GAA
SCHEMBL18114517 0.87 MAOA (0.45) MAOAMAOBOPRM1OPRL1GAA
SCHEMBL4896837 0.87 GAA (0.51) MAOAMAOBGAAALDH1A1KMT2A
SCHEMBL10602994 0.87 MAOA (0.50) MAOAMAOBOPRM1OPRL1GAA
SCHEMBL30613092 0.87 ALDH1A1 (0.41) MAOAMAOBOPRM1OPRL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 641 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119688896-B Cell membrane bionic nano-recognition material and preparation method and application thereof 陕西科技大学 2026-05-12 CN claimed
CN-119033823-B Probiotic product and preparation method and application thereof 南昌大学 2025-04-22 CN claimed
CN-119753095-A Antibiotic resistance gene detection method for click chemistry coupling biosensing 华东师范大学 2025-04-04 CN claimed
CN-119688896-A Cell membrane bionic nano-recognition material and preparation method and application thereof 陕西科技大学 2025-03-25 CN claimed
CN-119033823-A Probiotic product and preparation method and application thereof 南昌大学 2024-11-29 CN claimed
CN-118759172-A Preparation method of allophycocyanin immunofluorescence probe 宝天生物科技(上海)有限公司 2024-10-11 CN claimed
US-20240327322-A1 Crosslinked Polymers with Tunable Coefficients of Thermal Expansion NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC 2024-10-03 US claimed
EP-3601609-B1 ARTICLES AND METHODS INVOLVING DETECTION OF BINDING CHARLES RIVER LABORATORIES INC (US) 2024-07-03 EP claimed
CN-117327262-B Responsive nano-drug carrier and preparation and application thereof 中山大学附属第三医院 2024-06-14 CN claimed
US-20240181074-A1 PEGYLATED T CELL ENGAGER WITH DUAL SPECIFICITIES TO CD3 AND CD19 SHENZHEN ENDURING BIOTECH, LTD. (CN) 2024-06-06 US claimed
EP-3274473-A1 METHODS AND COMPOSITIONS FOR SINGLE MOLECULE COMPOSITION LOADING Pacific Biosciences of California, Inc. (US) 2018-01-31 EP claimed
US-20180023115-A1 Nanopore Detection of Target Polynucleotides From Sample Background ONTERA INC. 2018-01-25 US claimed
WO-2017173392-A1 NANOPORE DISCRIMINATION OF TARGET POLYNUCLEOTIDES FROM SAMPLE BACKGROUND BY FRAGMENTATION AND PAYLOAD BINDING Two Pore Guys, Inc. (US) 2017-10-05 WO claimed
EP-3202424-A1 KIT FOR FORMULATION OF LIPOSOMAL DOXORUBICIN MODIFIED WITH BIOACTIVE PEPTIDES FOR SELECTIVE TARGETING OF RECEPTORS OVEREXPRESSED BY CANCER CELLS Invectors S.r.l. (IT) 2017-08-09 EP claimed
US-20170209474-A1 KIT FOR FORMULATION OF LIPOSOMAL DOXORUBICIN MODIFIED WITH BIOACTIVE PEPTIDES FOR SELECTIVE TARGETING OF RECEPTORS OVEREXPRESSED BY CANCER CELLS INVECTORS S.R.L. (IT) 2017-07-27 US claimed
WO-2017120536-A1 POLYETHYLENIMINE (PEI)-POLYPEPTIDE CONJUGATES AND METHODS OF USE THEREOF APG THERAPEUTICS, INC. (US) 2017-07-13 WO claimed
WO-2016154345-A1 METHODS AND COMPOSITIONS FOR SINGLE MOLECULE COMPOSITION LOADING PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2016-09-29 WO claimed
WO-2016154337-A2 METHOD FOR IDENTIFICATION AND ENUMERATION OF NUCLEIC ACID SEQUENCES, EXPRESSION, SPLICE VARIANT, TRANSLOCATION, COPY, OR DNA METHYLATION CHANGES USING COMBINED NUCLEASE, LIGASE, POLYMERASE, TERMINAL TRANSFERASE, AND SEQUENCING REACTIONS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2016-09-29 WO claimed
WO-2016126746-A1 NANOPORE DETECTION OF TARGET POLYNUCLEOTIDES FROM SAMPLE BACKGROUND Two Pore Guys, Inc. (US) 2016-08-11 WO claimed
EP-0606344-B1 SOLID-FORM ADDITIVE SYSTEMS DISPERSIBLE IN AQUEOUS MEDIA AND METHOD FOR THEIR PREPARATION EASTMAN CHEM CO (US) 1996-01-03 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240181074-A1 PEGYLATED T CELL ENGAGER WITH DUAL SPECIFICITIES TO CD3 AND CD19 CD4, CD2, CD22 MAOA 4195/4885MAOB 1196/4885OPRM1 2614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.