SCHEMBL2687101

SCHEMBL2687101

Clc1[c]cc(Br)nc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL193743 0.74
SCHEMBL9479870 0.74
SCHEMBL9098933 0.70
SCHEMBL3029075 0.70
SCHEMBL18668181 0.70
SCHEMBL1727145 0.70
SCHEMBL2799371 0.70
SCHEMBL14694175 0.70
SCHEMBL2794625 0.67 SIRT6 (0.52)
SCHEMBL14471469 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113549069-A Kinase inhibitor 重庆复创医药研究有限公司 2021-10-26 CN disclosed
CN-108779117-B Kinase inhibitor 重庆复创医药研究有限公司 2021-08-31 CN disclosed
EP-2462124-B9 MESOIONIC PESTICIDES DU PONT (US) 2017-08-23 EP disclosed
WO-2017114351-A1 CERTAIN PROTEIN KINASE INHIBITORS Chongqing Fochon Pharmaceutical Co., Ltd. (CN) 2017-07-06 WO disclosed
US-9596856-B2 Mesoionic pesticides E I DU PONT DE NEMOURS AND COMPANY (US) 2017-03-21 US disclosed
WO-2016058544-A1 INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) SYROS PHARMACEUTICALS, INC. (US) 2016-04-21 WO disclosed
US-9314025-B2 Mixtures of mesoionic pesticides E I DU PONT DE NEMOURS AND COMPANY (US) 2016-04-19 US disclosed
US-20160066577-A1 MESOIONIC PESTICIDES FMC CORPORATION 2016-03-10 US disclosed
US-9210932-B2 Mesoionic pesticides E I DU PONT DE NEMOURS AND COMPANY (US) 2015-12-15 US disclosed
US-9108965-B2 Malonic acid di-salts and a method for preparing malonyl dihalides E I DU PONT DE NEMOURS AND COMPANY (US) 2015-08-18 US disclosed
US-20140206536-A1 MESOIONIC PESTICIDES E I DU PONT DE NEMOURS AND COMPANY (US) 2014-07-24 US disclosed
US-20140187776-A1 MIXTURES OF MESOIONIC PESTICIDES E I DU PONT DE NEMOURS AND COMPANY (US) 2014-07-03 US disclosed
US-8722690-B2 Mesoionic pesticides E I DU PONT DE NEMOURS AND COMPANY (US) 2014-05-13 US disclosed
US-8697707-B2 Mixtures of mesoionic pesticides E I DU PONT DE NEMOURS AND COMPANY (US) 2014-04-15 US disclosed
EP-2462124-B1 MESOIONIC PESTICIDES DU PONT (US) 2014-01-08 EP disclosed
US-20130190171-A1 MESOIONIC PYRIDO [1, 2-A] PYRIMIDINE PESTICIDES E I DU PONT DE NEMOURS AND COMPANY (US) 2013-07-25 US disclosed
US-20120277100-A1 MESOIONIC PESTICIDES FMC CORPORATION 2012-11-01 US disclosed
US-20120115722-A1 MIXTURES OF MESOIONIC PESTICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-05-10 US disclosed
CN-101855209-A Alkyl sulfone derivative DAIICHI SANKYO CO LTD 2010-10-06 CN disclosed
EP-2204365-A1 ALKYLSULFONE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2010-07-07 EP disclosed