Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | KCNN3 | Q9UGI6 | 5/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 4/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 5/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.32 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26870905 | 0.83 | PDE10A (0.51) | PDE10AKCNN3CDK2CCNT1CDK9 | |
| SCHEMBL12953881 | 0.82 | PDE10A (0.61) | PDE10AKCNN3KCNN1KCNN2 | |
| SCHEMBL26871132 | 0.78 | PDE10A (0.49) | PDE10AKCNN3CDK2CCNT1CDK9 | |
| SCHEMBL26872867 | 0.77 | CDK9 (0.55) | CDK2CCNT1CDK9CCNA2CCNA1 | |
| SCHEMBL26872870 | 0.72 | CDK9 (0.62) | CDK2CCNT1CDK9CCNA2CCNA1 | |
| SCHEMBL8573496 | 0.70 | PDE10A (0.57) | PDE10AKCNN3CDK2CCNT1CDK9 | |
| SCHEMBL26870956 | 0.70 | PDE10A (0.53) | PDE10AKCNN3KCNN1KCNN2 | |
| SCHEMBL29869 | 0.69 | PDE10A (1.00) | PDE10AKCNN3CDK2CHEK1CCNA2 | |
| SCHEMBL5466448 | 0.69 | PDE10A (0.56) | PDE10ACDK2CCNT1CDK9CHEK1 | |
| SCHEMBL26871188 | 0.69 | PDE10A (0.51) | PDE10AKCNN3CDK2CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282868-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-11-29 | — | — | EP | disclosed |