Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 20/20 | 0.58 |
| ▸ | CCNT1 | O60563 | 19/20 | 0.58 |
| ▸ | CDK4 | P11802 | 6/20 | 0.49 |
| ▸ | CCND1 | P24385 | 6/20 | 0.49 |
| ▸ | CDK7 | P50613 | 5/20 | 0.49 |
| ▸ | CCNH | P51946 | 4/20 | 0.49 |
| ▸ | CDK2 | P24941 | 4/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.45 |
| ▸ | CDK3 | Q00526 | 3/20 | 0.45 |
| ▸ | CDK1 | P06493 | 2/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.45 |
| ▸ | CDK13 | Q14004 | 2/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.43 |
| ▸ | CCNK | O75909 | 1/20 | 0.43 |
| ▸ | CDK14 | O94921 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26871851 | 0.90 | CDK9 (0.58) | CDK9CCNT1CDK4CCND1CDK7 | |
| SCHEMBL26872867 | 0.85 | CDK9 (0.55) | CDK9CCNT1CDK4CCND1CDK7 | |
| SCHEMBL26871658 | 0.85 | CDK9 (0.65) | CDK9CCNT1CDK4CCND1CDK7 | |
| SCHEMBL26872897 | 0.83 | CDK9 (0.62) | CDK9CCNT1CDK4CCND1CDK7 | |
| SCHEMBL26871783 | 0.83 | CDK9 (0.56) | CDK9CCNT1CDK4CCND1CDK7 | |
| SCHEMBL24418850 | 0.81 | CDK9 (0.56) | CDK9CCNT1CDK4CCND1CDK7 | |
| SCHEMBL21877739 | 0.79 | CDK9 (0.66) | CDK9CCNT1CDK4CCND1CDK7 | |
| SCHEMBL24174235 | 0.79 | CDK9 (0.62) | CDK9CCNT1CDK4CCND1CDK7 | |
| SCHEMBL26872817 | 0.78 | RAB9A (0.46) | CDK9CCNT1CDK2 | |
| SCHEMBL26872849 | 0.77 | CSNK2B (0.45) | CDK9CCNT1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282868-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-11-29 | — | — | EP | disclosed |