SCHEMBL2687199

SCHEMBL2687199

CCCCSc1ccc(-c2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.55
HDAC2 Q92769 1/20 0.55
SLC2A1 P11166 1/20 0.55
ALDH1A1 P00352 5/20 0.50
MAPT P10636 4/20 0.50
NPSR1 Q6W5P4 3/20 0.50
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.50
MAPK1 P28482 2/20 0.48
XDH P47989 1/20 0.46
PTGES O14684 1/20 0.43
ALOX5 P09917 1/20 0.43
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
LMNA P02545 2/20 0.43
HTT P42858 1/20 0.43
PLK1 P53350 1/20 0.43
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10528199 0.92 HDAC1 (0.56) HDAC1HDAC2SLC2A1ALDH1A1MAPT
SCHEMBL10525993 0.92 SLC2A1 (0.62) HDAC1HDAC2SLC2A1ALDH1A1MAPT
SCHEMBL12432111 0.88 ALDH1A1 (0.52) HDAC1HDAC2SLC2A1ALDH1A1MAPT
SCHEMBL4179998 0.87 ALDH1A1 (0.64) HDAC1HDAC2ALDH1A1MAPTNPSR1
SCHEMBL575895 0.87 ALDH1A1 (0.64) HDAC1HDAC2ALDH1A1MAPTNPSR1
Ammonia Solution, Strong SCHEMBL19133464 0.85 ALDH1A1 (0.61) HDAC1HDAC2ALDH1A1MAPTNPSR1
Fluoride SCHEMBL27793289 0.85 ALDH1A1 (0.61) HDAC1HDAC2ALDH1A1MAPTNPSR1
SCHEMBL10527738 0.85 SLC2A1 (0.60) HDAC1HDAC2SLC2A1ALDH1A1MAPT
Fluoride SCHEMBL943089 0.85 ALDH1A1 (0.61) HDAC1HDAC2ALDH1A1MAPTNPSR1
SCHEMBL5887468 0.85 MAOA (0.62) SLC2A1ALDH1A1MAPTNPSR1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8168565-B2 Thermal recording adhesive label RICOH COMPANY, LTD. (JP) 2012-05-01 US disclosed
US-20090209419-A1 THERMAL RECORDING ADHESIVE LABEL RICOH COMPANY, LTD. (JP) 2009-08-20 US disclosed
US-6846619-B2 Dye dispersion liquid and thermosensitive recording material using the same RICOH COMPANY, LTD. (JP) 2005-01-25 US disclosed
EP-1243437-B1 Leuco dye dispersion liquid and thermosensitive recording material using the same RICOH KK (JP) 2004-11-17 EP disclosed
US-20030060366-A1 Dye dispersion liquid and thermosensitive recording material using the same RICOH COMPANY, LTD. 2003-03-27 US disclosed
EP-1243437-A1 Leuco dye dispersion liquid and thermosensitive recording material using the same Ricoh Company, Ltd. (JP) 2002-09-25 EP disclosed