Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17520050 | 0.96 | LMNA (0.59) | LMNAALDH1A1TDP1SLC6A3KMT2A | |
| SCHEMBL2687492 | 0.84 | LMNA (0.58) | LMNAALDH1A1TDP1SLC6A3KMT2A | |
| SCHEMBL29050130 | 0.81 | LMNA (0.58) | LMNAALDH1A1TDP1SLC6A3KMT2A | |
| SCHEMBL2689216 | 0.81 | LMNA (0.58) | LMNAALDH1A1TDP1SLC6A3KMT2A | |
| SCHEMBL16338679 | 0.79 | LMNA (0.56) | LMNAALDH1A1TDP1SLC6A3KMT2A | |
| Ethyl Benzoate SCHEMBL25388294 | 0.78 | LMNA (0.70) | LMNAALDH1A1TDP1SLC6A3KMT2A | |
| Ethyl Benzoate SCHEMBL55674 | 0.78 | LMNA (0.70) | LMNAALDH1A1TDP1SLC6A3KMT2A | |
| Ethyl Benzoate SCHEMBL2762273 | 0.78 | LMNA (0.70) | LMNAALDH1A1TDP1SLC6A3KMT2A | |
| SCHEMBL15070606 | 0.78 | LMNA (0.55) | LMNAALDH1A1TDP1SLC6A3KMT2A | |
| SCHEMBL253482 | 0.77 | TDP1 (0.49) | LMNAALDH1A1TDP1SLC6A3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8222357-B2 | Procatalyst composition with multiple internal donor having silyl ester and method | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC (US) | 2012-07-17 | — | — | US | disclosed |
| US-8088872-B2 | Procatalyst composition including silyl ester internal donor and method | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-01-03 | — | — | US | disclosed |
| US-20100130710-A1 | Procatalyst Composition with Multiple Internal Donor Having Silyl Ester and Method | W. R. GRACE & CO.-CONN. | 2010-05-27 | — | — | US | disclosed |
| US-20100130709-A1 | Procatalyst Composition Including Silyl Ester Internal Donor and Method | W. R. GRACE & CO.-CONN. | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130709-A1 | Procatalyst Composition Including Silyl Ester Internal Donor and Method | GNE, NANS, ELANE | LMNA 1109/4885ALDH1A1 677/4885TDP1 2949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.