Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2687492 | 0.83 | LMNA (0.58) | ALDH1A1LMNATDP1TSHRMAPK1 | |
| SCHEMBL2689216 | 0.80 | LMNA (0.58) | ALDH1A1LMNATDP1ADRB2ADRB1 | |
| SCHEMBL29050130 | 0.80 | LMNA (0.58) | ALDH1A1LMNATDP1ADRB2ADRB1 | |
| SCHEMBL202613 | 0.78 | TSHR (0.46) | ALDH1A1LMNATDP1ADRB2ADRB1 | |
| Benzoic Acid 2-Methylpropyl Ester SCHEMBL20530394 | 0.77 | TSHR (0.69) | ALDH1A1LMNATDP1ADRB2ADRB1 | |
| Benzoic Acid 2-Methylpropyl Ester SCHEMBL298176 | 0.77 | TSHR (0.69) | ALDH1A1LMNATDP1ADRB2ADRB1 | |
| Benzoic Acid 2-Methylpropyl Ester SCHEMBL28242226 | 0.75 | TSHR (0.67) | ALDH1A1LMNATDP1ADRB2ADRB1 | |
| Benzoic Acid 2-Methylpropyl Ester SCHEMBL27827529 | 0.75 | TSHR (0.67) | ALDH1A1LMNATDP1ADRB2ADRB1 | |
| SCHEMBL15070606 | 0.74 | LMNA (0.55) | ALDH1A1LMNATDP1ADRB2ADRB1 | |
| Benzoic Acid 1-(3-Methyl)Butyl Ester SCHEMBL132524 | 0.74 | LMNA (0.65) | ALDH1A1LMNATDP1ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350143-B1 | PROCATALYST COMPOSITION MULTIPLE INTERNAL DONOR HAVING SILYL ESTER AND METHOD | GRACE W R & CO (US) | 2016-02-17 | — | — | EP | disclosed |
| EP-2350144-B1 | PROCATALYST COMPOSITION INCLUDING SILYL ESTER INTERNAL DONOR AND METHOD | GRACE W R & CO (US) | 2015-07-15 | — | — | EP | disclosed |
| US-8222357-B2 | Procatalyst composition with multiple internal donor having silyl ester and method | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC (US) | 2012-07-17 | — | — | US | disclosed |
| US-8088872-B2 | Procatalyst composition including silyl ester internal donor and method | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-01-03 | — | — | US | disclosed |
| US-20100130710-A1 | Procatalyst Composition with Multiple Internal Donor Having Silyl Ester and Method | W. R. GRACE & CO.-CONN. | 2010-05-27 | — | — | US | disclosed |
| US-20100130709-A1 | Procatalyst Composition Including Silyl Ester Internal Donor and Method | W. R. GRACE & CO.-CONN. | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130709-A1 | Procatalyst Composition Including Silyl Ester Internal Donor and Method | GNE, NANS, ELANE | ALDH1A1 677/4885LMNA 1109/4885TDP1 2949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.