SCHEMBL2687386

SCHEMBL2687386

C/C=C(/C)C1=CCCCC1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 2/20 0.45
HDAC2 Q92769 2/20 0.45
HDAC8 Q9BY41 2/20 0.45
HDAC6 Q9UBN7 2/20 0.45
CTSK P43235 1/20 0.41
HDAC3 O15379 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38
GSTP1 P09211 1/20 0.33
CCR2 P41597 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2687392 1.00 HDAC4 (0.45) HDAC4HDAC2HDAC8HDAC6CTSK
SCHEMBL2688324 1.00 HDAC4 (0.45) HDAC4HDAC2HDAC8HDAC6CTSK
SCHEMBL14988865 0.78 HDAC2 (0.50) HDAC4HDAC2HDAC8HDAC6CTSK
SCHEMBL3133166 0.78
SCHEMBL20556760 0.78 HDAC2 (0.47) HDAC4HDAC2HDAC8HDAC6CTSK
SCHEMBL24044324 0.77 HDAC4 (0.45) HDAC4HDAC2HDAC8HDAC6CTSK
SCHEMBL8894092 0.76 HDAC2 (0.48) HDAC4HDAC2HDAC8HDAC6CTSK
SCHEMBL1053257 0.74
SCHEMBL310711 0.74
SCHEMBL2689130 0.74 HDAC2 (0.47) HDAC4HDAC2HDAC8HDAC6CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8168842-B2 Process for the alkylation of a cycloalkene SHELL OIL COMPANY (US) 2012-05-01 US disclosed
US-20090227824-A1 PROCESS FOR THE ALKYLATION OF A CYCLOALKENE SHELL OIL COMPANY 2009-09-10 US disclosed
WO-2007135047-A1 PROCESS FOR THE ALKYLATION OF A CYCLOALKENE SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2007-11-29 WO disclosed
EP-0005406-B1 ELECTROCHEMICAL CATALYTIC SYSTEM AND PROCESS FOR THE ELECTROCHEMICAL SELECTIVE DIMERISATION OF CONJUGATED DIOLEFINS Société Chimique des Charbonnages (FR) 1981-09-30 EP disclosed
US-4238301-A CATALYST COMPRISING DINITROSYLIRON CHLORIDE OR IRON CHLORIDE AND NITRIC OXIDE; OXYGEN-FREE; CONTROLLING THE VOLTAGE CDF CHIMIE (FR) 1980-12-09 US disclosed
EP-0005406-A2 Electrochemical catalytic system and process for the electrochemical selective dimerisation of conjugated diolefins Société Chimique des Charbonnages (FR) 1979-11-14 EP disclosed