Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 17/20 | 0.43 |
| ▸ | CDK9 | P50750 | 17/20 | 0.43 |
| ▸ | CDK4 | P11802 | 7/20 | 0.43 |
| ▸ | CCND1 | P24385 | 7/20 | 0.43 |
| ▸ | CDK2 | P24941 | 7/20 | 0.43 |
| ▸ | CDK1 | P06493 | 6/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 6/20 | 0.43 |
| ▸ | CDK3 | Q00526 | 6/20 | 0.43 |
| ▸ | CDK6 | Q00534 | 4/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.43 |
| ▸ | CDK7 | P50613 | 4/20 | 0.43 |
| ▸ | CCNH | P51946 | 4/20 | 0.43 |
| ▸ | CCNC | P24863 | 2/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
| ▸ | CCNK | O75909 | 1/20 | 0.34 |
| ▸ | CDK14 | O94921 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26871568 | 0.83 | CDK9 (0.62) | CCNT1CDK9CDK4CCND1CDK2 | |
| SCHEMBL26871566 | 0.81 | RAB9A (0.47) | CCNT1CDK9CDK4CCND1CDK2 | |
| SCHEMBL26873656 | 0.80 | CCNT1 (0.58) | CCNT1CDK9CDK4CCND1CDK2 | |
| SCHEMBL21946105 | 0.76 | CCNT1 (0.54) | CCNT1CDK9CDK4CCND1CDK2 | |
| SCHEMBL26872750 | 0.74 | CCNT1 (0.44) | CCNT1CDK9CDK4CCND1CDK2 | |
| SCHEMBL26871370 | 0.72 | CDK9 (0.52) | CCNT1CDK9CDK4CCND1CDK2 | |
| SCHEMBL26872077 | 0.71 | CDK9 (0.63) | CCNT1CDK9CDK4CCND1CDK2 | |
| SCHEMBL26872690 | 0.71 | RAB9A (0.46) | CCNT1CDK9CDK4CCND1CDK2 | |
| SCHEMBL26874333 | 0.71 | CCNT1 (0.60) | CCNT1CDK9CDK4CCND1CDK2 | |
| SCHEMBL26871882 | 0.71 | CDK9 (0.66) | CCNT1CDK9CDK4CCND1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282868-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-11-29 | — | — | EP | disclosed |