Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26870881 | 0.82 | KDM4E (0.37) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL26871557 | 0.76 | CCNT1 (0.47) | KDM4EALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL26867726 | 0.75 | CCNA2 (0.48) | CDK5CDK5R1CYP1A2 | |
| SCHEMBL26871561 | 0.74 | CDK9 (0.54) | CDK5CDK5R1CYP1A2 | |
| SCHEMBL17470351 | 0.73 | KDM4E (0.50) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL10388599 | 0.73 | KDM4E (0.66) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL20534145 | 0.69 | KDM4E (0.60) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL26869093 | 0.67 | CHEK1 (0.52) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL26867729 | 0.67 | CDK2 (0.44) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL26869091 | 0.67 | KDM4E (0.35) | KDM4EALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282868-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-11-29 | — | — | EP | disclosed |