SCHEMBL2687904

SCHEMBL2687904

CN1C(C)(C)CC(OC(=O)C(Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)C(=O)OC2CC(C)(C)N(C)C(C)(C)C2)CC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.40
HMGCR P04035 2/20 0.40
PKM P14618 1/20 0.40
HTT P42858 1/20 0.40
ALDH1A1 P00352 8/20 0.39
KDM4E B2RXH2 4/20 0.39
MAPT P10636 4/20 0.39
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
TSHR P16473 4/20 0.36
LMNA P02545 2/20 0.36
POLB P06746 1/20 0.36
THRB P10828 1/20 0.36
HPGD P15428 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
USP2 O75604 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11863851 0.95 GAA (0.39) GAAHMGCRPKMHTTALDH1A1
SCHEMBL7759198 0.91 GAA (0.37) GAAHMGCRPKMHTTALDH1A1
SCHEMBL11521649 0.90 GAA (0.39) GAAHMGCRPKMHTTALDH1A1
SCHEMBL334874 0.89 GAA (0.39) GAAHMGCRPKMHTTALDH1A1
SCHEMBL11492147 0.89 ALDH1A1 (0.41) GAAHMGCRPKMHTTALDH1A1
SCHEMBL11521647 0.88 GAA (0.38) GAAHMGCRPKMHTTALDH1A1
SCHEMBL9245857 0.88 GAA (0.35) GAAHMGCRPKMHTTALDH1A1
SCHEMBL11489217 0.86 HMGCR (0.43) GAAHMGCRPKMHTTALDH1A1
SCHEMBL11494088 0.86 GAA (0.35) GAAHMGCRPKMHTTALDH1A1
SCHEMBL10000628 0.85 GAA (0.39) GAAHMGCRPKMHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8721946-B2 Low-sticky additive package for automotive interior applications BOREALIS AG (AT) 2014-05-13 US disclosed
EP-1967541-B1 Process for producing cellulose ester film KONICA MINOLTA OPTO INC (JP) 2013-07-03 EP disclosed
US-8361354-B2 Optical film, method of manufacturing the optical film, polarizing plate protective film, polarizing plate using the protective film, and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2013-01-29 US disclosed
US-8361354-B2 Optical film, method of manufacturing the optical film, polarizing plate protective film, polarizing plate using the protective film, and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2013-01-29 US disclosed
US-20120298007-A1 PROCESS FOR PRODUCING CELLULOSE ESTER FILM, CELLULOSE ESTER FILM, POLARIZATION PLATE AND DISPLAY UNIT KONICA MINOLTA OPTO, INC. (JP) 2012-11-29 US disclosed
US-20120298007-A1 PROCESS FOR PRODUCING CELLULOSE ESTER FILM, CELLULOSE ESTER FILM, POLARIZATION PLATE AND DISPLAY UNIT KONICA MINOLTA OPTO, INC. (JP) 2012-11-29 US disclosed
US-20120115995-A1 AUTOMOTIVE INTERIOR ARTICLE WITH REDUCED SMELL BOREALIS AG (AT) 2012-05-10 US disclosed
US-20110045210-A1 Optical film, method of manufacturing the optical film, polarizing plate protective film,polarizing plate using the protective film,and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-02-24 US disclosed
US-20110045210-A1 Optical film, method of manufacturing the optical film, polarizing plate protective film,polarizing plate using the protective film,and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-02-24 US disclosed
US-20100286310-A1 LOW-STICKY ADDITIVE PACKAGE FOR AUTOMOTIVE INTERIOR APPLICATIONS BOREALIS AG (AT) 2010-11-11 US disclosed
US-20090306361-A1 PROCESS FOR PRODUCING CELLULOSE ESTER FILM, CELLULOSE ESTER FILM, POLARIZATION PLATE AND DISPLAY UNIT KONICA MINOLTA OPTO, INC. (JP) 2009-12-10 US disclosed
US-20090306361-A1 PROCESS FOR PRODUCING CELLULOSE ESTER FILM, CELLULOSE ESTER FILM, POLARIZATION PLATE AND DISPLAY UNIT KONICA MINOLTA OPTO, INC. (JP) 2009-12-10 US disclosed
US-20090226641-A1 Composition, Optical Film, Method of Producing Optical Film, Polarizing Plate and Liquid Crystal Display Apparatus KONICA MINOLTA OPTO, INC. (JP) 2009-09-10 US disclosed
US-20090226641-A1 Composition, Optical Film, Method of Producing Optical Film, Polarizing Plate and Liquid Crystal Display Apparatus KONICA MINOLTA OPTO, INC. (JP) 2009-09-10 US disclosed
US-20090142515-A1 Cellulose Ester Film, Process for Producing Cellulose Ester Film, Optical Film, Polarization Plate and Liquid Crystal Display Unit KONICA MINOLTA OPTO, INC. (JP) 2009-06-04 US disclosed
US-20090142515-A1 Cellulose Ester Film, Process for Producing Cellulose Ester Film, Optical Film, Polarization Plate and Liquid Crystal Display Unit KONICA MINOLTA OPTO, INC. (JP) 2009-06-04 US disclosed
EP-1964881-A1 COMPOSITION, OPTICAL FILM, PROCESS FOR PRODUCING OPTICAL FILM, POLARIZATION PLATE AND LIQUID CRYSTAL DISPLAY APPARATUS Konica Minolta Opto, Inc. (JP) 2008-09-03 EP disclosed
US-4198334-A HEAT, LIGHT, OXIDATION RESISTANCE, PLASTICS CIBA-GEIGY CORPORATION (US) 1980-04-15 US disclosed