Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557005 | 1.00 | HTR1A (0.70) | HTR1AMAOB | |
| SCHEMBL8554502 | 0.98 | HTR1A (0.68) | HTR1AMAOB | |
| SCHEMBL6339624 | 0.98 | HTR1A (0.69) | HTR1AMAOB | |
| SCHEMBL3174057 | 0.97 | HTR1A (0.68) | HTR1AMAOB | |
| SCHEMBL12124720 | 0.97 | HTR1A (0.68) | HTR1AMAOB | |
| SCHEMBL1569172 | 0.95 | HTR1A (0.69) | HTR1AMAOB | |
| SCHEMBL2362765 | 0.93 | HTR1A (0.68) | HTR1AMAOB | |
| SCHEMBL5824979 | 0.93 | HTR1A (0.68) | HTR1AMAOB | |
| SCHEMBL8557594 | 0.92 | HTR1A (0.62) | HTR1AMAOB | |
| SCHEMBL14028451 | 0.91 | HTR1A (0.79) | HTR1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142518-B1 | 3,4-DIHYDROQUINAZOLINE DERIVATIVES | DONGWOO SYNTECH CO LTD (KR) | 2012-05-02 | — | — | EP | disclosed |
| US-8168646-B2 | 3,4-dihydroquinazoline derivatives | DONGWOO SYNTECH CO., LTD. (KR) | 2012-05-01 | — | — | US | disclosed |
| US-8168646-B2 | 3,4-dihydroquinazoline derivatives | DONGWOO SYNTECH CO., LTD. (KR) | 2012-05-01 | — | — | US | disclosed |
| US-8168646-B2 | 3,4-dihydroquinazoline derivatives | DONGWOO SYNTECH CO., LTD. (KR) | 2012-05-01 | — | — | US | disclosed |
| US-20100120803-A1 | 3,4-DIHYDROQUINAZOLINE DERIVATIVES | DONGWOO SYNTECH CO., LTD. (KR) | 2010-05-13 | — | — | US | disclosed |
| US-20100120803-A1 | 3,4-DIHYDROQUINAZOLINE DERIVATIVES | DONGWOO SYNTECH CO., LTD. (KR) | 2010-05-13 | — | — | US | disclosed |
| US-20100120803-A1 | 3,4-DIHYDROQUINAZOLINE DERIVATIVES | DONGWOO SYNTECH CO., LTD. (KR) | 2010-05-13 | — | — | US | disclosed |
| EP-2142518-A1 | 3,4-DIHYDROQUINAZOLINE DERIVATIVES | Dongwoo Syntech Co., Ltd. (KR) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008136631-A1 | 3,4-DIHYDROQUINAZOLINE DERIVATIVES | DONGWOO SYNTECH CO., LTD. (KR) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008136631-A1 | 3,4-DIHYDROQUINAZOLINE DERIVATIVES | DONGWOO SYNTECH CO., LTD. (KR) | 2008-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120803-A1 | 3,4-DIHYDROQUINAZOLINE DERIVATIVES | CACNA1I, CACNA1G, CACNA1H | HTR1A 1119/4885MAOB 3324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.