Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2686945 | 0.88 | TAAR1 (0.41) | TAAR1CYP11B2CYP11B1PPARGPPARA | |
| SCHEMBL13994398 | 0.79 | TAAR1 (0.47) | TAAR1CYP11B2CYP11B1 | |
| 2-Phenylimidazole SCHEMBL9783251 | 0.76 | NISCH (0.51) | TAAR1CYP11B2CYP17A1CYP3A4CYP11B1 | |
| SCHEMBL27652491 | 0.74 | TAAR1 (0.64) | TAAR1CYP11B2CYP17A1CYP3A4CYP11B1 | |
| SCHEMBL30704326 | 0.74 | TAAR1 (0.64) | TAAR1CYP11B2CYP17A1CYP3A4CYP11B1 | |
| SCHEMBL13994399 | 0.73 | ACHE (0.44) | TAAR1CYP11B2CYP17A1CYP3A4CYP11B1 | |
| SCHEMBL28102063 | 0.72 | TAAR1 (0.61) | TAAR1CYP11B2CYP17A1CYP3A4CYP11B1 | |
| Biphenyl SCHEMBL25183774 | 0.72 | TAAR1 (0.67) | TAAR1CYP11B2CYP17A1CYP3A4CYP11B1 | |
| SCHEMBL275277 | 0.72 | CALM1 (0.43) | TAAR1 | |
| SCHEMBL29451178 | 0.72 | TAAR1 (0.67) | TAAR1CYP11B2CYP17A1CYP3A4CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8089658-B2 | Image forming device and method for controlling toner temperature on photoreceptor when a toner image is exposed to light | FUJI XEROX CO., LTD. (JP) | 2012-01-03 | — | — | US | disclosed |