Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 3/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26686466 | 0.79 | CCNK (0.54) | AXLPRKCINUDT1CDK9AURKA | |
| SCHEMBL3492132 | 0.78 | KDR (0.50) | NUDT1AURKAAURKBDAOCCNK | |
| SCHEMBL26889101 | 0.77 | AXL (0.40) | AXLPRKCINUDT1CDK9AURKA | |
| SCHEMBL30571033 | 0.75 | AXL (0.44) | AXLPRKCINUDT1CDK9AURKA | |
| SCHEMBL21429079 | 0.75 | NUDT1 (0.59) | AXLPRKCINUDT1CDK9AURKA | |
| SCHEMBL31420473 | 0.75 | NUDT1 (0.59) | AXLPRKCINUDT1CDK9AURKA | |
| SCHEMBL3415919 | 0.75 | AXL (0.44) | AXLPRKCINUDT1CDK9AURKA | |
| SCHEMBL31240636 | 0.74 | CDK9 (0.40) | MAOAMAOBCDK9CCNT1CDC7 | |
| SCHEMBL21428737 | 0.72 | KDM5A (0.42) | AXLPRKCIMAOANUDT1CDK9 | |
| SCHEMBL30716680 | 0.72 | KDM5A (0.42) | AXLPRKCIMAOANUDT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |