Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 1/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26889438 | 0.92 | HRH3 (0.44) | DRD2DRD4DRD3HRH3CDC7 | |
| SCHEMBL26686635 | 0.87 | CCNK (0.48) | DRD2DRD4DRD3CDC7PIM1 | |
| SCHEMBL26889301 | 0.86 | CCNK (0.45) | DRD2DRD4DRD3HRH3CDC7 | |
| SCHEMBL26889371 | 0.86 | CCNK (0.45) | DRD2DRD4DRD3HRH3CDC7 | |
| SCHEMBL26686338 | 0.80 | CCNK (0.47) | DRD2DRD4DRD3CDC7PIM1 | |
| SCHEMBL26889381 | 0.78 | CCNK (0.54) | SIGMAR1CCNKCDK12 | |
| SCHEMBL26889338 | 0.76 | CCNK (0.58) | DRD2DRD4DRD3CDC7PIM1 | |
| SCHEMBL26686140 | 0.76 | DAO (0.39) | DRD2DRD4DRD3CDC7PIM1 | |
| SCHEMBL30633400 | 0.75 | KDM4E (0.55) | CYP1A2 | |
| SCHEMBL26686575 | 0.74 | CCNK (0.58) | CDC7PIM1CDK9CHEK1CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |