Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 5/20 | 0.58 |
| ▸ | CDK12 | Q9NYV4 | 5/20 | 0.58 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.44 |
| ▸ | CDK9 | P50750 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KDM4B | O94953 | 1/20 | 0.40 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26889381 | 0.95 | CCNK (0.54) | CCNKCDK12METAP2HRH4ALK | |
| SCHEMBL26889371 | 0.86 | CCNK (0.45) | CCNKCDK12METAP2CDK9PIM1 | |
| SCHEMBL26889301 | 0.86 | CCNK (0.45) | CCNKCDK12METAP2CDK9PIM1 | |
| SCHEMBL26889354 | 0.86 | CCNK (0.45) | CCNKCDK12METAP2HRH4CDK9 | |
| SCHEMBL26686575 | 0.84 | CCNK (0.58) | CCNKCDK12METAP2CDK9PIM1 | |
| SCHEMBL26889310 | 0.82 | CCNK (0.42) | CCNKCDK12CDK9PIM1CDC7 | |
| SCHEMBL24596893 | 0.82 | CDK9 (0.57) | ALKCDK9PIM1CDC7TNIK | |
| SCHEMBL26889405 | 0.76 | DRD2 (0.46) | CCNKCDK12CDK9PIM1CDC7 | |
| SCHEMBL30571033 | 0.75 | AXL (0.44) | CCNKCDK12ALKCDK9PIM1 | |
| SCHEMBL3415919 | 0.75 | AXL (0.44) | CCNKCDK12ALKCDK9PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |