Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26858665 | 0.82 | HCAR2 (0.34) | MLYCDHCAR2 | |
| SCHEMBL26897139 | 0.81 | HCAR2 (0.32) | HCAR2 | |
| SCHEMBL26897006 | 0.81 | HCAR2 (0.32) | HCAR2 | |
| SCHEMBL12058917 | 0.77 | HCAR2 (0.39) | MLYCDHCAR2 | |
| SCHEMBL26859996 | 0.74 | HCAR2 (0.34) | MLYCDHCAR2 | |
| SCHEMBL21209899 | 0.71 | HCAR2 (0.38) | MLYCDHCAR2 | |
| SCHEMBL16996968 | 0.70 | HCAR2 (0.36) | MLYCDHCAR2 | |
| SCHEMBL21610747 | 0.70 | HCAR2 (0.36) | MLYCDHCAR2 | |
| SCHEMBL8447951 | 0.70 | HCAR2 (0.36) | MLYCDHCAR2 | |
| SCHEMBL14037127 | 0.69 | MLYCD (0.37) | MLYCDHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230374022-A1 | INHIBITORS OF PARG | 858 THERAPEUTICS, INC. | 2023-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230374022-A1 | INHIBITORS OF PARG | PARG, PLG, SERPINB1 | MLYCD 2580/4885HCAR2 1982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.