Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | ASGR1 | P07306 | 6/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24256587 | 0.89 | HCRTR2 (0.36) | HCRTR2ASGR1 | |
| SCHEMBL26899389 | 0.83 | HCRTR2 (0.42) | HCRTR2ASGR1 | |
| SCHEMBL29384147 | 0.83 | HCRTR2 (0.42) | HCRTR2ASGR1 | |
| SCHEMBL26899408 | 0.83 | HCRTR2 (0.42) | HCRTR2ASGR1 | |
| SCHEMBL24256533 | 0.83 | HCRTR2 (0.42) | HCRTR2ASGR1 | |
| SCHEMBL26899493 | 0.83 | HCRTR2 (0.42) | HCRTR2ASGR1 | |
| SCHEMBL24256524 | 0.83 | HCRTR2 (0.42) | HCRTR2ASGR1 | |
| SCHEMBL24256586 | 0.83 | HCRTR2 (0.42) | HCRTR2ASGR1 | |
| SCHEMBL24724923 | 0.79 | ASGR1 (0.43) | HCRTR2ASGR1 | |
| SCHEMBL26899410 | 0.79 | NFKB1 (0.37) | HCRTR2ASGR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240072809-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2024-02-29 | — | — | US | disclosed |
| US-11819551-B2 | ASGPR-binding compounds for the degradation of extracellular proteins | AVILAR THERAPEUTICS, INC. (US) | 2023-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11819551-B2 | ASGPR-binding compounds for the degradation of extracellular proteins | ASGR1, ENGASE, FCGR2A | HCRTR2 3763/4885ASGR1 1/4885TDP1 3930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.